post-SSRI sexual dysfunction

English

(medicine, pathology) A permanent condition of physical and psychological sexual anhedonia, among other symptoms, that occurs in around 1 in 200 people who have consumed SRI drugs (SSRIs, SNRIs, etcetera), more often afflicting introverts and autism-spectrum individuals, and which is caused by the permanent desensitization of some serotonin receptors.
Synonyms: PSSD (initialism), post-SSRI syndrome
- 2018 June 8, anonymous author, “My life in sex: ‘After taking antidepressants, my genitals felt numb’”, in The Guardian‎^[1]:
  I've since discovered this side-effect isn't uncommon and has a name: PSSD (post-SSRI sexual dysfunction). I know men who also suffer with PSSD and struggle with the same genital numbness and anorgasmia, coupled with erectile dysfunction.