Allows you to use curative spells.Description
Cleansing materia is a 
Magic Materia in Final Fantasy VII Remake and "Episode INTERmission", equipped to heal negative status effects. It provides 
Poisona, which cures 
Poison; Esuna, which cures all negative statuses; and Resist, which provides resistance to status effects to a character.
Obtained
A cleansing materia can first be purchased from the Sector 7 Slums shop after completing "Rat Problem" in Chapter 3, "Home Sweet Slum", for a discounted 300 gil. Later on they can be purchased from vending machines and materia shops after reaching Chapter 5, "Dogged Pursuit", for 1500 gil apiece.
In INTERmission, cleansing materia is sold in the Sector 7 Slums item shop, and all vending machines.
Stats
Growth
| Level | AP required | Effect |
|---|---|---|
| 1 | 0 | Poisona |
| 2 | 300 | Esuna |
| 3 | 900 | Resist |
Abilities
| Magic | MP | Effect |
|---|---|---|
| Poisona | 3 | Cure Poison.
|
| Esuna | 12 | Cure negative status effects. |
| Resist | 8 | Grant the  Resist buff, providing resistance to negative status effects.
|
Use
Cleansing materia grants three spells to cure status ailments. Initially available is Poisona, the cheapest spell to cast, costing only 3 MP. Esuna is more expensive to cast, but cures all negative status effects. Resist grants the Resist buff to a character, protecting them from negative statuses.
Against enemies that frequently inflict negative status effects, such as sahagins, cleansing materia can be crucial to prevent a battle from going downhill. Resist can be the most MP efficient if a character will be on the receiving end of many negative statuses. Additionally, because spells from cleansing materia do not rely on a character's attributes, the materia can be given to any character with a spare slot, or to those with the MP to cast it.
If a character wishes to preserve materia slots, cleansing materia can be replicated by items that also cure negative statuses, and several accessories provide resistance to negative statuses also. Against Poison, the Healing Materia at level 3 provides Regen, which can negate Poison; if paired with 
Magnify Materia, Regen can be applied to all characters, negating any need to cast Poisona, and potentially being more MP efficient. Chakra can also cure Poison. Warding Materia can also be paired with some magic materia to provide resistance to some effects, though this takes up more materia slots.
Relying on cleansing materia can be expensive for MP. This is particularly problematic in hard difficulty, when items are not available and MP is harder to restore. In these circumstances, using accessories is preferable. Furthermore, many of the enemy attacks that inflict negative statuses are telegraphed and can be dodged.
The cleansing materia's level is assessed for the Chocobo Sam questline at Wall Market during "The Town That Never Sleeps" where Cloud helps the pharmacist deliver medicine.
In "Episode INTERmission", though the materia is available for purchase, there is no particular need for it; with only two party members, the player will likely want to use their equipment slots for other materia.