| Protagonist | Niko Bellic |
| Central characters | Roman Bellic | Little Jacob | Dimitri Rascalov† | Jimmy Pegorino† | Bernie Crane | Darko Brevic |
| Main characters | Mallorie Bardas | Vladimir Glebov† | Mikhail Faustin† | Brucie Kibbutz | Manny Escuela† | Elizabeta Torres | Patrick McReary | Francis McReary | Gerald McReary | Derrick McReary† | Kate McReary | Playboy X | Dwayne Forge | Ray Boccino† | Phil Bell | United Liberty Paper contact | Jon Gravelli† |
| Radio DJs | Beatrix Fontaine | DJ Green Lantern | DJ Mister Cee†| DJ Premier | François K | Roy Ayers | Femi Kuti | Gary Sheen | Jane Labrador | Jeffron James | Lazlow Jones | Marcel LeMuir | Roy Haynes† | Ryan McFallon | Karl Lagerfeld† | Jimmy Gestapo | Iggy Pop | Bobby Konders | Juliette Lewis | Daddy Yankee | Carl Bradshaw | Vaughn Harper† | Ruslana Lyzhychko |
| Supporting characters | Michelle/Karen | Ilyena Faustin | Isaac Roth† | Kim Young-Guk† | Ray Bulgarin† | Jay Hamilton† | Jim Fitzgerald† | Johnny Klebitz† | Gordon Sargent | Michael Keane† | Maureen McReary | Luis Fernando Lopez | Anthony Corrado† | Stevie | The Fixer | Tony Prince | Bryce Dawkins | Eugene Reaper† | Mohammed | Zorba Philippidis† |
| Minor characters | Adam Dimayev† | Aiden O'Malley† | Alejandra | Alonzo | Andrei† | Angela Allan† | Angie Pegorino | Anna Faustin | Anthony† | Benny† | Bledar Morina† | Bobby Jefferson | Brett | Bucky Sligo† | Catch | Charlie† | Charles Matteo† | Christopher Tibbits | Chuck Williams-Jones | City Official | Clarence's Associate† | Dardan Petrela† | Dave Bosoy† | Doctor Rosem | Eduard Borodin† | Felipe | Frankie Garone† | Frankie Gallo | Jason Michaels† | Jayvon Simson† | Jermaine Andrews | Jimmy | John | John Barbosa† | Joseph DiLeo† | Joseph Kaplan | Kalem† | Karen (Lawyers) | Katerina | Lamon | Larissa Slalom | Lavar Davis† | Lenny Petrovic† | Lori Williams-Jones† | Luca Silvestri† | Lyle Rivas† | Marco Bonnaro† | Mark† | Marlon Bridges† | Mickey | Mitch | Mori Green† | Mr. Fuk's Rice Box manager | Muscovski | Oleg Minkov† | Peter Marchetti† | Priest | Sal† | Sheila Stafford† | Shirley† | Slimeball | Talbot Daniels | Teddy Benavidez† | Thai Prostitute | The Blackmailer† | The Doctor | The Hater† | The Kidnapper† | Kidnapper's Accomplice† | The Truck Driver† | Tom Goldberg† | Tom Rivas† | Tony† | Tony Black† | Trunchez Brothers† | Unnamed Russian Goon | Vasily | Vera | Mason Waylon | Wedding Assassin | Wilson Taylor Sr.† | Unnamed Lost MC Biker† | Sergei | Ed the Mate | Isaac's girlfriend | Westdyke Memorial Hospital Receptionist |
| Girlfriends | Alexandra Chilton | Carmen Ortiz | Kiki Jenkins |
| Random characters | Brian Meech | Mel | Real Badman | Hossan Ramzy | Sara | Pathos | Jeff Harlingford | Marnie Allen | Eddie Low† | Cherise Glover | Cherise Glover's Boyfriend | Clarence Little† | Gracie Ancelotti | Ilyena Faustin | Ivan Bytchkov |
| Petrovic Mafiya | Kenny Petrovic | Lenny Petrovic† |Mrs. Petrovic | Petrovic's Daughter | Anton† | Anton the Rat† | Boris† | Georgi† | Igor | Ivo† | Rami Yalon | Sergey† | Vanya | Vasil† | Vitali | Yuri |
| Most Wanted criminals | Alonso Goralski† | Antonio Rivette† | Barry Lamora† | Bert Reker† | Christov Mahonvic† | Danny Hatmaker† | Darren Covey† | Fernando Tisdel† | Freddy Paparo† | Frederick Harrison† | Glenn Lushbaugh† | Jimmy Kand† | Juan Haimo† | Keenan Burdett† | Leo Brodell† | Lino Friddell† | Marty Boldenow† | Maxwell Caughlin† | Mervin Eskuchen† | Noel Katsuda† | Phil Bacerra† | Preston Pecinovsky† | Rodrigo Stavnes† | Rodney McEniry† | Scott Guzowski† | Sergi Szerbin† | Shon Kikuchi† | Simon Nashly† | Tommy Francovic† | Tyler Pickrel† |
| Mentioned characters | Chan Jaoming† | Fifteen Man Squad | George Lawton | Hsin Jaoming | Huang Lee | Hugh Djas | Joe Lawton | Lester Arnold | Lester Leroc | Mallorie's Cousin | Marko | Mr. Wong | Niko's Brother† | Phyllis | Rudy D'Avanzo† | Rudy D'Avanzo's Father† | Thomas Piretta | Wu "Kenny" Lee† | Zhou Ming† | Tom Pireni | Natalya Shironova |
| Other characters | Rob | Vicki | Yusuf Amir | Troy Harder | Lola Del Rio | Jase | Milica Bellic | Roman's Child | Mila Tadic | Jerry Kapowitz | Horatio Humboldt | Gloria Hole | Steve | Kelly |
| Beta characters | Alyssa Funke | Bradly Narlock | Cletus Luzell | Dick Godley | Marcel Hevas | Marty Connor | Tommy Francini | Wilbert Wetterer |
† denotes Deceased, Italics denotes a status determined by the player's choice
Characters in GTA IV | Category:Characters in GTA IV | Grand Theft Auto IV | Category:Characters |