(Q21108125)

hierarchical database ID heuristic

Transporter Classification Database ID

1.A.9.2.1

Neurotransmitter-gated ion-channel ligand-binding domain superfamily

1 October 2019

part of

1 reference

Neurotransmitter-gated ion-channel transmembrane domain superfamily

1 reference

5-hydroxytryptamine 3 receptor, A subunit

1 reference

cysteine loop ligand-gated ion channel receptor

1 reference

Transporter Classification Database ID

1.A.9.2.1

2 October 2019

hierarchical database ID heuristic

Neurotransmitter-gated ion-channel transmembrane domain, protein family

1 reference

inferred from protein domain or family

Neurotransmitter-gated ion-channel ligand-binding domain, protein family

1 reference

inferred from protein domain or family

Neurotransmitter-gated ion-channel, conserved site, protein family

1 reference

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

IPI

1 reference

8 April 2019

Characterization of the novel human serotonin receptor subunits 5-HT3C,5-HT3D, and 5-HT3E

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

ligand-gated ion channel activity

IPI

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

1 reference

8 April 2019

serotonin binding

1 reference

8 April 2019

Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

extracellular ligand-gated ion channel activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46098&geneProductId=UniProtKB:P46098

1 reference

16 July 2018

serotonin-gated cation-selective channel activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

8 April 2019

Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

8 April 2019

The 5-HT3B subunit is a major determinant of serotonin-receptor function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

ion channel activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

1 reference

8 April 2019

transmembrane signaling receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

1 reference

8 April 2019

cell component

cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

1 reference

8 April 2019

plasma membrane

TAS

synapse

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46098&geneProductId=UniProtKB:P46098

1 reference

16 July 2018

axon

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

cell junction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

1 reference

8 April 2019

soma

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

serotonin-activated cation-selective channel complex

1 reference

8 April 2019

The 5-HT3B subunit is a major determinant of serotonin-receptor function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

cleavage furrow

1 reference

8 April 2019

From midbody protein-protein interaction network construction to novel regulators in cytokinesis

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

integral component of postsynaptic membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

integral component of presynaptic membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

integral component of plasma membrane

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

neuron projection

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

biological process

response to cocaine

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

cellular response to growth factor stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

response to ethanol

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

positive regulation of ion transmembrane transporter activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

signal transduction

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46098&geneProductId=UniProtKB:P46098

ion transmembrane transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46098&geneProductId=UniProtKB:P46098

1 reference

16 July 2018

serotonin receptor signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

signal transduction

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

chemical synaptic transmission

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46098&geneProductId=UniProtKB:P46098

regulation of membrane potential

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

nervous system process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46098

physically interacts with

1 reference

218

17 August 2016

1 reference

5

English

1-(3-chlorophenyl)biguanide

17 August 2016

has use

agonist

1 reference

2287

17 August 2016

1 reference

173

17 August 2016

1 reference

2296

17 August 2016

1 reference

2285

17 August 2016

1 reference

2297

17 August 2016

1 reference

2286

17 August 2016

1 reference

241

17 August 2016

1 reference

2290

17 August 2016

1 reference

2301

17 August 2016

1 reference

2294

17 August 2016

1 reference

7351

17 August 2016

1 reference

2366

17 August 2016

1 reference

2298

English

object of statement has role

17 August 2016

dolasetron

antagonist

1 reference

Open _targets Platform

14 August 2023

https://platform.open_targets.org/drug/CHEMBL2368925

zimeldine

object of statement has role

antagonist

1 reference

Open _targets Platform

14 August 2023

https://platform.open_targets.org/drug/CHEMBL37744

metoclopramide hydrochloride hydrate

object of statement has role

antagonist

1 reference

Open _targets Platform

14 August 2023

https://platform.open_targets.org/drug/CHEMBL1200940

has part(s)

Neurotransmitter-gated ion-channel transmembrane domain

1 reference

Neurotransmitter-gated ion-channel ligand-binding domain

1 reference

Neurotransmitter-gated ion-channel, conserved site

1 reference

http://www.uniprot.org/uniprot/P23979.txt?version=134

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 November 2015

Transporter Classification Database ID

1.A.9.2.1

2 references

Transporter Classification database

13 March 2020

Transporter Classification database