(Q422438)

Gene Ontology release 2019-11-16

cellular response to chloroquine

subject has role

reactant

1 reference

Gene Ontology release 2019-11-16

0 references

1 reference

Medical Subject Headings

15 March 2018

Chloroquine.svg
512 × 286; 3 KB

0 references

mass

319.182 dalton

1 reference

chloroquine (English)

17 November 2016

319.18152551199995 dalton

1 reference

inferred from SMILES

chemical formula

C₁₈H₂₆ClN₃

1 reference

chloroquine (English)

17 November 2016

canonical SMILES

CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl

1 reference

chloroquine (English)

17 November 2016

CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12

1 reference

inferred from InChI

pKa

10.18

1 reference

Hydroxychloroquine is much less active than chloroquine against chloroquine-resistant Plasmodium falciparum, in agreement with its physicochemical properties

10.2

1 reference

Chloroquine and hydroxychloroquine binding to melanin: Some possible consequences for pathologies

1 reference

14 February 2018

World Health Organisation international non-proprietary name

chloroquine (English)

1 reference

Lasionectrin, a naphthopyrone from a Lasionectria sp.

chloroquine (English)

3 October 2016

1 reference

Pseudopestalotiopsis theae

1 reference

Chlorotheolides A and B, Spiroketals Generated via Diels-Alder Reactions in the Endophytic Fungus Pestalotiopsis theae

Pestalotiopsis theae

1 reference

Chlorotheolides A and B, Spiroketals Generated via Diels-Alder Reactions in the Endophytic Fungus Pestalotiopsis theae

Grewia bilamellata

1 reference

Antimalarial compounds from Grewia bilamellata.

Acronychia pubescens

1 reference

Acrotrione: An Oxidized Xanthene from the Roots of Acronychia pubescens

Caldora penicillata

1 reference

Hoshinoamides A and B, Acyclic Lipopeptides from the Marine Cyanobacterium Caldora penicillata

Oscillatoria

2 references

Isolation and Total Synthesis of Mabuniamide, a Lipopeptide from an Okeania sp. Marine Cyanobacterium

Ikoamide, an Antimalarial Lipopeptide from an Okeania sp. Marine Cyanobacterium

Xenorhabdus nematophila

1 reference

Xenortide Biosynthesis by Entomopathogenic Xenorhabdus nematophila

Heterosporicola chenopodii

1 reference

MDN-0104, an antiplasmodial betaine lipid from Heterospora chenopodii

Okeania

2 references

Isolation and Total Synthesis of Mabuniamide, a Lipopeptide from an Okeania sp. Marine Cyanobacterium

Ikoamide, an Antimalarial Lipopeptide from an Okeania sp. Marine Cyanobacterium

medical condition treated

1 reference

13 December 2016

1 reference

13 December 2016

1 reference

Plasmodium falciparum malaria

13 December 2016

1 reference

13 December 2016

1 reference

13 December 2016

1 reference

significant drug interaction

13 December 2016

amiodarone

1 reference

High-priority drug–drug interactions for use in electronic health records

anagrelide

1 reference

High-priority drug–drug interactions for use in electronic health records

arsenic trioxide

1 reference

High-priority drug–drug interactions for use in electronic health records

astemizole

1 reference

High-priority drug–drug interactions for use in electronic health records

azithromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

bepridil

1 reference

High-priority drug–drug interactions for use in electronic health records

chlorpromazine

1 reference

High-priority drug–drug interactions for use in electronic health records

cisapride

1 reference

High-priority drug–drug interactions for use in electronic health records

(RS)-citalopram

1 reference

High-priority drug–drug interactions for use in electronic health records

clarithromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

cocaine

1 reference

High-priority drug–drug interactions for use in electronic health records

disopyramide

1 reference

High-priority drug–drug interactions for use in electronic health records

dofetilide

1 reference

High-priority drug–drug interactions for use in electronic health records

domperidone

1 reference

High-priority drug–drug interactions for use in electronic health records

dronedarone

1 reference

High-priority drug–drug interactions for use in electronic health records

droperidol

1 reference

High-priority drug–drug interactions for use in electronic health records

erythromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

escitalopram

1 reference

High-priority drug–drug interactions for use in electronic health records

flecainide

1 reference

High-priority drug–drug interactions for use in electronic health records

halofantrine

1 reference

High-priority drug–drug interactions for use in electronic health records

haloperidol

1 reference

High-priority drug–drug interactions for use in electronic health records

ibutilide

1 reference

High-priority drug–drug interactions for use in electronic health records

mesoridazine

1 reference

High-priority drug–drug interactions for use in electronic health records

(RS)-methadone

1 reference

High-priority drug–drug interactions for use in electronic health records

reference URL

https://www.drugs.com/drug-interactions/methadone-index.html

moxifloxacin

1 reference

High-priority drug–drug interactions for use in electronic health records

ondansetron

1 reference

High-priority drug–drug interactions for use in electronic health records

pentamidine

1 reference

High-priority drug–drug interactions for use in electronic health records

pimozide

1 reference

High-priority drug–drug interactions for use in electronic health records

probucol

1 reference

High-priority drug–drug interactions for use in electronic health records

procainamide

1 reference

High-priority drug–drug interactions for use in electronic health records

quinidine

1 reference

High-priority drug–drug interactions for use in electronic health records

sevoflurane

1 reference

High-priority drug–drug interactions for use in electronic health records

sotalol

1 reference

High-priority drug–drug interactions for use in electronic health records

sparfloxacin

1 reference

High-priority drug–drug interactions for use in electronic health records

(RS)-sulpiride

1 reference

High-priority drug–drug interactions for use in electronic health records

terfenadine

1 reference

High-priority drug–drug interactions for use in electronic health records

thioridazine

1 reference

High-priority drug–drug interactions for use in electronic health records

cimetidine

side effect

seizure

1 reference

sourcing circumstances

probably

A reference set of clinically relevant adverse drug-drug interactions

cimetidine

side effect

psychomotor agitation

1 reference

sourcing circumstances

probably

A reference set of clinically relevant adverse drug-drug interactions

cimetidine

side effect

pulseless electrical activity

1 reference

sourcing circumstances

probably

A reference set of clinically relevant adverse drug-drug interactions

physically interacts with

MAS related GPR family member X1

subject has role

agonist

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5535

LiverTox likelihood score

17 August 2016

route of administration

oral administration

0 references

LiverTox toxicity likelihood category D

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Chloroquine

2 February 2017

1 reference

DNA polymerase inhibitors

1 reference

5 March 2018

disease-modifying antirheumatic drug

1 reference

on focus list of Wikimedia project

Medical Subject Headings

15 March 2018

1 reference

Medical Subject Headings

15 March 2018

0 references

1 reference

0 references

WikiProject Zika Corpus

0 references

WikiProject COVID-19

0 references

different from

hydroxychloroquine

1 reference

imported from Wikimedia project

French Wikipedia

Wikimedia import URL

https://fr.wikipedia.org/w/index.php?title=Chloroquine&oldid=169490115

chloroquine phosphate

0 references

Commons category

Chloroquine

0 references

catalog

CAS COVID-19 Anti-Viral Candidate Compounds

0 references

Identifiers

J9U ID

987007551569205171

1 reference

National Library of Israel

Library of Congress authority ID

1 reference

25 March 2020

0 references

InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)

1 reference

chloroquine (English)

17 November 2016

3 references

chloroquine (English)

17 November 2016

ChEBI release 2020-09-01

2 references

chloroquine (English)

17 November 2016

https://commonchemistry.cas.org/detail?cas_rn=54-05-7

10 April 2021

58175-87-4

reason for deprecated rank

applies to other chemical entity

intended subject of deprecated statement

0 references

1 reference

Chloroquine (English)

17 November 2016

2 references

chloroquine (English)

17 November 2016

Reaxys registry number

482809

1 reference

chloroquine (English)

3 October 2016

Gmelin number

781126

0 references

ChEBI ID

3638

mapping relation type

2 references

CHLOROQUINE (English)

17 November 2016

International Chemical Identifier

InChI

InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)

1 reference

CHLOROQUINE (English)

17 November 2016

2 references

inferred from InChIKey

MSBNK-Fac_Eng_Univ_Tokyo-JP003161

1 reference

MassBank accession ID

0 references

MSBNK-Waters-WA000965

0 references

MSBNK-Waters-WA000966

0 references

MSBNK-Waters-WA000967

0 references

MSBNK-Waters-WA000968

0 references

MSBNK-Waters-WA000969

0 references

MSBNK-Waters-WA000970

0 references

SPLASH

splash10-000i-9320000000-2663c398ede2e502ca34

0 references

NMRShiftDB structure ID

10019311

1 reference

HSDB ID

3029

1 reference

Hazardous Substances Data Bank

28 October 2019

CHLOROQUINE (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

1 reference

chloroquine (English)

ECHA Substance Infocard ID

17 November 2016

100.000.175

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.000.175

27 December 2018

Chloroquine (English)

quotation

CAS no.: 54-05-7 (English)

1 reference

Guide to Pharmacology Ligand ID

Chloroquine (English)

publication date

17 November 2015

5535

2 references

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5535

chloroquine (English)

17 November 2016

https://www.guidetopharmacology.org/coronavirus.jsp

22 April 2020

reference URL

MeSH descriptor ID

D002738

Chloroquine

0 references

MeSH tree code

D03.633.100.810.050.180

0 references

RxNorm ID

2393

1 reference

chloroquine (English)

17 November 2016

DrugBank ID

DB00608

1 reference

Human Metabolome Database ID

HMDB0014746

2 references

inferred from InChIKey

KNApSAcK ID

C00058826

2 references

inferred from InChIKey

2 references

chloroquine (English)

17 November 2016

MedlinePlus drug identifier

a682318

0 references

PatientsLikeMe treatment ID

chloroquine

0 references

NIAID ChemDB ID

000733

1 reference

imported from Wikimedia project

1 reference

chloroquine (English)

17 November 2016

0 references

1 reference

1 reference

chloroquine (English)

3 October 2016

1 reference

Immune Epitope Database and Analysis Resource

chloroquine (English)

3 October 2016

1 reference

IEDB Epitope ID

131785

electronic Essential Medicines List medicine ID

1 January 2022

275

0 references

Elhuyar ZTH ID

026657

0 references

Encyclopædia Britannica Online ID

science/chloroquine

France 24 topic ID (French)

chloroquine

0 references

0 references

1 reference

28 October 2013

0 references

Microsoft Academic ID

0 references

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

Store medisinske leksikon ID

klorokin

mapping relation type

exact match

klorokin

1 reference

Great Norwegian Encyclopedia

UK Parliament thesaurus ID

29 May 2020

468478

Chloroquine

0 references

UMLS CUI

C0008269

1 reference

chloroquine (English)

17 November 2016

0 references

0 references

WordNet 3.1 Synset ID

03026317-n

1 reference