Scream was one of the five Life Foundation Symbiotes that were forcefully spawned from the Venom symbiote.
Donna Diego was a mercenary hired by the Life Foundation. In order to fulfill her role as a superhuman officer for the corporation's future utopia, she was granted one of the 5 symbiotes forcibly spawned from the Venom symbiote.
Patricia Robertson was a twenty-four year-old lieutenant and communications specialist in the US Army who was bounded to a Venom symbiote's clone before it merged to Venom. Years later Patricia was overwhelmed and bonded to the Scream symbiote, and the two succumbed to the dark god Knull 's control.
Andi Benton was one of Flash Thompson's neighbors and students in Philadelphia. She was bound to the Mania symbiote and it's Hell-Mark. She had her symbiote stolen and later she was bonded to the Scream symbiote after Patricia sacrificed herself in order to protect Andi from Carnage.
