Open Heart: 8 (2)

Editorial

Low-grade metabolic acidosis as a driver of chronic disease: a 21st century public health crisis (26 October, 2021)
James J DiNicolantonio, James O'Keefe
Absorb BRS for in-stent restenosis: the final bow before (scaffold) collapse? (14 October, 2021)
Diego Arroyo, Stéphane Cook
Discordant moderate aortic stenosis: is it clinically important? (8 October, 2021)
Benoy Nalin Shah, Roxy Senior
Low-grade metabolic acidosis as a driver of insulin resistance (8 September, 2021)
James J DiNicolantonio, James H O'Keefe
Room for standardisation: the secondary prevention of coronary artery disease (19 August, 2021)
Rahul Bahl
Sealing the leaky pipeline: attracting and retaining women in cardiology (28 July, 2021)
F Aaysha Cader, Mirvat Alasnag, Shrilla Banerjee
Mechanical circulatory support in CS: device or patient? (22 July, 2021)
Nuccia Morici, Guido Tavazzi

Arrhythmias and sudden death

Original research: Atrial fibrillation detected at screening is not a benign condition: outcomes in screen-detected versus clinically detected atrial fibrillation. Results from the Prevention of Renal and Vascular End-stage Disease (PREVEND) study (30 December, 2021)
Victor W Zwartkruis, Bastiaan Geelhoed, Navin Suthahar, Stephan J L Bakker, Ron T Gansevoort, Isabelle C van Gelder, Rudolf A de Boer, Michiel Rienstra
Original research: Identifying patients with atrial fibrillation recurrences after two pulmonary vein isolation procedures (23 December, 2021)
Bart A Mulder, Meelad I H Al-Jazairi, Federico T Magni, Hessel F Groenveld, Robert G Tieleman, Ans C P Wiesfeld, Yong E S Tan, Isabelle C Van Gelder, Michiel Rienstra, Yuri Blaauw
Original research: Higher chances of survival to hospital admission after out-of-hospital cardiac arrest in patients with previously diagnosed heart disease (21 December, 2021)
Laura H van Dongen, Marieke T Blom, Sandra C M de Haas, Henk C P M van Weert, Petra J M Elders, Hanno L Tan
Original research: Cardiac stereotactic ablative radiotherapy for control of refractory ventricular tachycardia: initial UK multicentre experience (23 November, 2021)
Justin Lee, Matthew Bates, Ewen Shepherd, Stephen Riley, Michael Henshaw, Peter Metherall, Jim Daniel, Alison Blower, David Scoones, Michele Wilkinson, Neil Richmond, Clifford Robinson, Phillip Cuculich, Geoffrey Hugo, Neil Seller, Ruth McStay, Nicholas Child, Andrew Thornley, Nicholas Kelland, Philip Atherton, Clive Peedell, Matthew Hatton
Original research: Mortality and ventricular arrhythmia after acute myocarditis: a nationwide registry-based follow-up study (21 October, 2021)
Kristian Hay Kragholm, Filip Lyng Lindgren, Tomas Zaremba, Phillip Freeman, Niels Holmark Andersen, Sam Riahi, Manan Pareek, Lars Køber, Christian Torp-Pedersen, Peter Søgaard, Andreas Hagendorff, Bhupendar Tayal
Protocol: Investigating the efficacy of chest pressure for direct current cardioversion in atrial fibrillation: a randomised control trial protocol (Pressure-AF) (23 September, 2021)
David Ferreira, Philo Mikhail, Michael McGee, Andrew Boyle, Aaron Sverdlov, Maged William, Nicholas Jackson, Malcolm Barlow, James Leitch, Nicholas Collins, Thomas Ford, Bradley Wilsmore
Original research: Effect of moderate potassium-elevating treatment in long QT syndrome: the TriQarr Potassium Study (16 September, 2021)
Peter Marstrand, Kasim Almatlouh, Jørgen K Kanters, Claus Graff, Alex Hørby Christensen, Henning Bundgaard, Juliane Theilade
Original research: Paediatric/young versus adult patients with long QT syndrome (12 September, 2021)
Sharen Lee, Jiandong Zhou, Kamalan Jeevaratnam, Wing Tak Wong, Ian Chi Kei Wong, Chloe Mak, Ngai Shing Mok, Tong Liu, Qingpeng Zhang, Gary Tse
Original research: Implantable loop recorders in patients with heart disease: comparison between patients with and without syncope (13 August, 2021)
Amira Assaf, Rafi Sakhi, Michelle Michels, Jolien W Roos-Hesselink, Judith M A Verhagen, Rohit E Bhagwandien, Tamas Szili-Torok, Dominic Theuns, Sing-Chien Yap
Original research: Internationally validated score to predict the outcome of non-paroxysmal atrial fibrillation ablation: the ‘FLAME score’ (4 August, 2021)
Vennela Boyalla, Julian W E Jarman, Vias Markides, Wajid Hussain, Tom Wong, R Hardwin Mead, Gregory Engel, Melissa H Kong, Rob A Patrawala, Roger A Winkle
Original research: Anticoagulation trends in adults aged 65 years and over with atrial fibrillation: a cohort study (3 August, 2021)
Jenny Lund, Catherine L Saunders, Duncan Edwards, Jonathan Mant
Original research: Age-specific atrial fibrillation incidence, attributable risk factors and risk of stroke and mortality: results from the MORGAM Consortium (2 August, 2021)
Bente Morseth, Bastiaan Geelhoed, Allan Linneberg, Lars Johansson, Kari Kuulasmaa, Veikko Salomaa, Licia Iacoviello, Simona Costanzo, Stefan Söderberg, Teemu J Niiranen, Julie K K Vishram-Nielsen, Inger Njølstad, Tom Wilsgaard, Ellisiv B Mathiesen, Maja-Lisa Løchen, Tanja Zeller, Stefan Blankenberg, Francisco M Ojeda, Renate B Schnabel

Aortic and vascular disease

Original research: Patient perception and treatment convenience of dabigatran versus vitamin K antagonist when used for stroke prophylaxis in atrial fibrillation: Real-world Evaluation of Long-term Anticoagulant Treatment Experience (RE-LATE) study (2 December, 2021)
Young-Soo Lee, Yong Seog Oh, Eue-Keun Choi, Alan Koay Choon Chern, Panyapat Jiampo, Aurauma Chutinet, Dicky Armein Hanafy, Prabhav Trivedi, Dongmei Zhai
Original research:
Myocardial infarction coincides with increased NOX2 and N^ε-(carboxymethyl) lysine expression in the cerebral microvasculature
(24 November, 2021)
Amber Korn, Umit Baylan, Suat Simsek, Casper G Schalkwijk, Hans W M Niessen, Paul A J Krijnen
Original research: Aortic distensibility in Marfan syndrome: a potential predictor of aortic events? (26 October, 2021)
Mitzi M van Andel, Vivian de Waard, Janneke Timmermans, Arthur J H A Scholte, Maarten P van den Berg, Aeilko H Zwinderman, Barbara J M Mulder, Maarten Groenink
Original research: Valve disease and aortopathy associations of bicuspid aortic valve phenotypes differ between men and women (20 October, 2021)
Carl Granath, Salah A Mohamed, Christian Olsson, Michael Grattan, Luc Mertens, Anders Franco-Cereceda, Hanna M Björck

Basic and translational research

Review: AI and the cardiologist: when mind, heart and machine unite (23 December, 2021)
Antonio D'Costa, Aishwarya Zatale

Cardiac surgery

Original research: Short-term outcome after open-heart surgery for severe chronic rheumatic heart disease in a low-income country, with comparison with an historical control group: an observational study (10 August, 2021)
Ståle Wågen Hauge, Havard Dalen, Mette E Estensen, Robert Matongo Persson, Sintayehu Abebe, Desalew Mekonnen, Berhanu Nega, Atle Solholm, Marit Farstad, Nigussie Bogale, Torbjorn Graven, Niels-Erik Nielssen, Hege Kristin Brekke, Kjell Vikenes, Rune Haaverstad

Cardiac risk factors and prevention

Original research: Association of hypertension with mortality in patients hospitalised with COVID-19 (7 December, 2021)
Kunwardeep S Bhatia, Hari P Sritharan, Jonathan Ciofani, Justin Chia, Usaid K Allahwala, Karina Chui, Daniel Nour, Sheran Vasanthakumar, Dhanvee Khandadai, Pavithra Jayadeva, Rohan Bhagwandeen, David Brieger, Christopher Choong, Anthony Delaney, Girish Dwivedi, Benjamin Harris, Graham Hillis, Bernard Hudson, George Javorski, Nigel Jepson, Logan Kanagaratnam, George Kotsiou, Astin Lee, Sidney T Lo, Andrew I MacIsaac, Brendan McQuillan, Isuru Ranasinghe, Antony Walton, James Weaver, William Wilson, Andy S C Yong, John Zhu, William Van Gaal, Leonard Kritharides, Clara K Chow, Ravinay Bhindi
Original research:
CHA₂DS₂-VASc score stratifies mortality risk in patients with and without atrial fibrillation
(23 November, 2021)
Serge C Harb, Tom Kai Ming Wang, David Nemer, Yuping Wu, Leslie Cho, Venu Menon, Osama Wazni, Paul C Cremer, Wael Jaber
Review:
Vitamin K₂—a neglected player in cardiovascular health: a narrative review
(16 November, 2021)
Essa Hariri, Nicholas Kassis, Jean-Pierre Iskandar, Leon J Schurgers, Anas Saad, Omar Abdelfattah, Agam Bansal, Toshiaki Isogai, Serge C Harb, Samir Kapadia
Original research: Statin treatment and LDL-cholesterol treatment goal attainment among individuals with familial hypercholesterolaemia in primary care (26 October, 2021)
Barbara Iyen, Ralph K Akyea, Stephen Weng, Joe Kai, Nadeem Qureshi
Original research: Machine learning approaches improve risk stratification for secondary cardiovascular disease prevention in multiethnic patients (19 October, 2021)
Ashish Sarraju, Andrew Ward, Sukyung Chung, Jiang Li, David Scheinker, Fàtima Rodríguez
Original research: Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care (11 October, 2021)
Nadeem Qureshi, Ralph K Akyea, Brittany Dutton, Jo Leonardi-Bee, Steve E Humphries, Stephen Weng, Joe Kai
Original research: Interleukin 6 trans-signalling and the risk of future cardiovascular events in men and women (11 October, 2021)
Yasmin Miri, Karin Leander, Per Eriksson, Bruna Gigante, Louise Ziegler
Original research: Effectiveness of an impedance cardiography guided treatment strategy to improve blood pressure control in a real-world setting: results from a pragmatic clinical trial (27 September, 2021)
Luyan Wang, Yuan Lu, Hongyi Wang, Jianlei Gu, Zheng J Ma, Zheng Lian, Zhiying Zhang, Harlan Krumholz, Ningling Sun
Original research: Using genetics to detangle the relationships between red cell distribution width and cardiovascular diseases: a unique role for body mass index (14 September, 2021)
Timothy E Thayer, Shi Huang, Eric Farber-Eger, Joshua A Beckman, Evan L Brittain, Jonathan D Mosley, Quinn S Wells
Original research: Impact of risk factors for major cardiovascular diseases: a comparison of life-time observational and Mendelian randomisation findings (13 September, 2021)
Lars Lind, Martin Ingelsson, Johan Sundstrom, Johan Ärnlöv
Original research: Change in cardiovascular risk assessment tool and updated Norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: the Tromsø Study 2015–2016 (30 August, 2021)
Amalie Nilsen, Tove Aminda Hanssen, Knut Tore Lappegård, Anne Elise Eggen, Maja-Lisa Løchen, Randi Marie Selmer, Inger Njølstad, Tom Wilsgaard, Laila A Hopstock

Coronary artery disease

Original research: Association between non-alcoholic fatty liver disease and subclinical atherosclerosis in Western and Asian cohorts: an updated meta-analysis (21 December, 2021)
Mark Yu Zheng Wong, Jonathan Jiunn Liang Yap, Rehena Sultana, Mark Cheah, George Boon Bee Goh, Khung Keong Yeo
Original research: High levels of interleukin-6 are associated with final infarct size and adverse clinical events in patients with STEMI (21 December, 2021)
Ingvild Maria Tøllefsen, Christian Shetelig, Ingebjørg Seljeflot, Jan Eritsland, Pavel Hoffmann, Geir Øystein Andersen
Original research: Atrial fibrillation and clinical outcomes 1 to 3 years after myocardial infarction (15 December, 2021)
Anthony P Carnicelli, Ruth Owen, Stuart J Pocock, David B Brieger, Satoshi Yasuda, Jose Carlos Nicolau, Shaun G Goodman, Mauricio G Cohen, Tabassome Simon, Dirk Westermann, Katarina Hedman, Karolina Andersson Sundell, Christopher B Granger
Original research: Activation of PPCI team in the octogenarian and nonagenarians population: real-world single-centre experience (6 December, 2021)
Rajesh Kumar, Cormac O’Connor, Jathinder Kumar, Brain Kerr, Ihtisham Malik, Ciarrai Homer, Syed Abbas, Samer Arnous, Ihsan Ullah, Thomas John Kiernan
Original research: Implementation of an early rule-out pathway for myocardial infarction using a high-sensitivity cardiac troponin T assay (25 November, 2021)
Dennis Sandeman, Maaz B J Syed, Dorien M Kimenai, Kuan Ken Lee, Atul Anand, Shruti S Joshi, Lorraine Dinnel, Philip R Wenham, Ken Campbell, Mary Jarvie, Donna Galloway, Mhairi Anderson, Bappa Roy, Jack P M Andrews, Fiona E Strachan, Amy V Ferry, Andrew R Chapman, Sarah Elsby, Mark Francis, Robert Cargill, Anoop S V Shah, Nicholas L Mills
Original research: Impact of cancer on short-term in-hospital mortality after primary acute myocardial infarction (22 November, 2021)
Robert Zheng, Kenya Kusunose, Yuichiro Okushi, Yoshihiro Okayama, Michikazu Nakai, Yoko Sumita, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masataka Sata
Original research: Relationship of age, atherosclerosis and angiographic stenosis using artificial intelligence (16 November, 2021)
Rebecca Jonas, James Earls, Hugo Marques, Hyuk-Jae Chang, Jung Hyun Choi, Joon-Hyung Doh, Ae-Young Her, Bon Kwon Koo, Chang-Wook Nam, Hyung-Bok Park, Sanghoon Shin, Jason Cole, Alessia Gimelli, Muhammad Akram Khan, Bin Lu, Yang Gao, Faisal Nabi, Ryo Nakazato, U Joseph Schoepf, Roel S Driessen, Michiel J Bom, Randall C Thompson, James J Jang, Michael Ridner, Chris Rowan, Erick Avelar, Philippe Généreux, Paul Knaapen, Guus A de Waard, Gianluca Pontone, Daniele Andreini, Mouaz H Al-Mallah, Robert Jennings, Tami R Crabtree, Todd C Villines, James K Min, Andrew D Choi
Original research: Impact of a mass media campaign on presentations and ambulance use for acute coronary syndrome (18 October, 2021)
Kathryn Eastwood, Stuart Howell, Ziad Nehme, Judith Finn, Karen Smith, Peter Cameron, Dion Stub, Janet E Bray
Original research: Impaired autonomic function after incomplete revascularisation (11 October, 2021)
Richard Armstrong, Peter Wheen, Lisa Brandon, Ciarán Finucane, Rose Anne Kenny, Andrew Maree
Original research: Incidentally identified coronary artery calcium on non-contrast CT scan of the chest predicts major adverse cardiac events among hospital inpatients (11 October, 2021)
Christopher Yu, Austin C C Ng, Lloyd Ridley, Mekhala Anjaria, Silvan Meier, John Yiannikas, Leonard Kritharides, Christopher Naoum
Original research: Changes in ST segment elevation myocardial infarction hospitalisations in China from 2011 to 2015 (1 October, 2021)
Tianna Zhou, Xi Li, Yuan Lu, Karthik Murugiah, Xueke Bai, Shuang Hu, Yan Gao, Frederick A Masoudi, Harlan M Krumholz, Jing Li
Original research: Comparative evaluation of coronary disease burden: bicuspid valve disease is not atheroprotective (8 September, 2021)
Onur Baris Dolmaci, Antoine H G Driessen, Robert J M Klautz, Robert Poelmann, Jan H N Lindeman, Nimrat Grewal
Original research: Periodontitis is associated to increased systemic inflammation in postmyocardial infarction patients (12 August, 2021)
Ronaldo Lira-Junior, Elisabeth Almer Boström, Anders Gustafsson
Original research: Review of Irish patients meeting ST elevation criteria during the COVID-19 pandemic (3 August, 2021)
Luke Byrne, Roisin Gardiner, Patrick Devitt, Caleb Powell, Richard Armstrong, Sinead Teehan, Stephen O’Connor
Original research: Duration of dual antiplatelet therapy and stability of coronary heart disease: a 60 000-patient meta-analysis of randomised controlled trials (2 August, 2021)
Anda Bularga, Mohammed N Meah, Dimitrios Doudesis, Anoop S V Shah, Nicholas L Mills, David E Newby, Kuan Ken Lee
Original research: Vessel fractional flow reserve in assessment of non-culprit lesions in ST elevation myocardial infarction (2 August, 2021)
Chun Chin Chang, Ming Ju Chuang, Yin Hao Lee, Yi Lin Tsai, Ya Wen Lu, Ruey Hsing Chou, Cheng Hsueh Wu, Tse Min Lu, Po Hsun Huang, Shing Jong Lin
Original research: Effect of cardiosphere-derived cells on segmental myocardial function after myocardial infarction: ALLSTAR randomised clinical trial (7 July, 2021)
Mohammad R Ostovaneh, Raj R Makkar, Bharath Ambale-Venkatesh, Deborah Ascheim, Tarun Chakravarty, Timothy D Henry, Glen Kowalchuk, Frank V Aguirre, Dean J Kereiakes, Thomas J Povsic, Richard Schatz, Jay H Traverse, Janice Pogoda, Rachel D Smith, Linda Marbán, Eduardo Marbán, Joao A C Lima

Congenital heart disease

Original research: Long-term follow-up and sex differences in adults operated for tetralogy of Fallot (18 October, 2021)
Alessia Quattrone, Oyvind H Lie, Eirik Nestaas, Charlotte de Lange, Kirsti Try, Harald L Lindberg, Helge Skulstad, Gunnar Erikssen, Thor Edvardsen, Kristina Haugaa, Mette E Estensen
Original research: Long-term survival in patients with isolated pulmonary valve stenosis: a not so benign disease? (14 September, 2021)
Kristofer Skoglund, Annika Rosengren, Georgios Lappas, Maria Fedchenko, Zacharias Mandalenakis
Original research: Consultant staffing in UK congenital cardiac services: a 10-year survey of leavers and joiners (8 July, 2021)
David Steven Crossland, Richard Ferguson, Alan Magee, Petra Jenkins, Frances A Bulock, Andrew Parry, Sonya V Babu-Narayan, Aisling Carroll, Piers EF Daubeney, John Simpson

Health care delivery, economics and global health care

Original research: OpenSAFELY: impact of national guidance on switching anticoagulant therapy during COVID-19 pandemic (16 November, 2021)
The OpenSAFELY Collaborative, Helen J Curtis, Brian MacKenna, Alex J Walker, Richard Croker, Amir Mehrkar, Caroline Morton, Seb Bacon, George Hickman, Peter Inglesby, Chris Bates, David Evans, Tom Ward, Jonathan Cockburn, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Elizabeth Williamson, William Hulme, Laurie Tomlinson, Rohini Mathur, Henry Drysdale, Rosalind M Eggo, Angel Yun Wong, Harriet Forbes, John Parry, Frank Hester, Sam Harper, Ian Douglas, Liam Smeeth, Ben Goldacre
Original research: PRospective Evaluation of natriuretic peptide-based reFERral of patients with chronic heart failure in primary care (PREFER): a real-world study (20 October, 2021)
FD Richard Hobbs, Rizwan I Hussain, Cristina Vitale, Yigal M Pinto, Hector Bueno, Benoit Lequeux, Matthias Pauschinger, Michael Obermeier, Philippe C Ferber, Finn Gustafsson
Original research: Delivery preferences for psychological intervention in cardiac rehabilitation: a pilot discrete choice experiment (23 August, 2021)
Gemma Elizabeth Shields, Stuart Wright, Adrian Wells, Patrick Doherty, Lora Capobianco, Linda Mary Davies
Original research: Impact of COVID-19 on the imaging diagnosis of cardiac disease in Europe (5 August, 2021)
Michelle Claire Williams, Leslee Shaw, Cole B Hirschfeld, Pal Maurovich-Horvat, Bjarne L Nørgaard, Gianluca Pontone, Amelia Jimenez-Heffernan, Valentin Sinitsyn, Vladimir Sergienko, Alexey Ansheles, Jeroen J Bax, Ronny Buechel, Elisa Milan, Riemer H J A Slart, Edward Nicol, Chiara Bucciarelli-Ducci, Yaroslav Pynda, Nathan Better, Rodrigo Cerci, Sharmila Dorbala, Paolo Raggi, Todd C Villines, Joao Vitola, Eli Malkovskiy, Benjamin Goebel, Yosef Cohen, Michael Randazzo, Thomas N B Pascual, Maurizio Dondi, Diana Paez, Andrew J Einstein
Original research: Work-life balance: a comparison of women in cardiology and other specialties (21 July, 2021)
Anastasia Vlachadis Castles, Sonya Burgess, Kristy Robledo, Anna L Beale, Sinjini Biswas, Louise Segan, Sarah Gutman, Swati Mukherjee, Angeline Leet, Sarah Zaman
Original research: Cardiac rehabilitation patients experiences and understanding of group metacognitive therapy: a qualitative study (14 July, 2021)
Rebecca McPhillips, Lora Capobianco, Bethany Grace Cooper, Zara Husain, Adrian Wells
Original research: Associations between physical activity, sedentary behaviour and left ventricular structure and function from the Echocardiographic Study of Latinos (ECHO-SOL) (14 July, 2021)
Andrew E Berdy, Bharathi Upadhya, Sonia Ponce, Katrina Swett, Richard B Stacey, Robert Kaplan, Priscilla M Vasquez, Qibin Qi, Neil Schneiderman, Barry E Hurwitz, Martha L Daviglus, Mayank Kansal, Kelly R Evenson, Carlos J Rodriguez

Heart failure and cardiomyopathies

Original research: Impaired right ventricular function in long-term survivors of allogeneic haematopoietic stem-cell transplantation (21 December, 2021)
Richard John Massey, Phoi Phoi Diep, Marta Maria Burman, Anette Borger Kvaslerud, Lorentz Brinch, Svend Aakhus, Lars Gullestad, Ellen Ruud, Jan Otto Beitnes
Original research: Prognostic importance of the Controlling Nutritional Status (CONUT) score in patients undergoing cardiac resynchronisation therapy (28 October, 2021)
Yukitoshi Ikeya, Yuki Saito, Toshiko Nakai, Rikitake Kogawa, Naoto Otsuka, Yuji Wakamatsu, Sayaka Kurokawa, Kimie Ohkubo, Koichi Nagashima, Yasuo Okumura
Original research: Mild aortic valve disease and the diastolic pressure–volume relationship in heart failure with preserved ejection fraction (20 October, 2021)
Frederik H Verbrugge, Yogesh N V Reddy, Mackram F Eleid, Grace Lin, Daniel Burkhoff, Barry A Borlaug
Protocol: Rationale and design of the preserved versus reduced ejection fraction biomarker registry and precision medicine database for ambulatory patients with heart failure (PREFER-HF) study (18 October, 2021)
Andrew Abboud, Austin Nguonly, Asher Bean, Kemar J Brown, Roy F Chen, David Dudzinski, Neyat Fiseha, Melvin Joice, Davis Kimaiyo, Mackenzie Martin, Christy Taylor, Kevin Wei, Megan Welch, Daniel A Zlotoff, James L Januzzi, Hanna K Gaggin
Original research: Nationwide prevalence and characteristics of transthyretin amyloid cardiomyopathy in Sweden (13 October, 2021)
Rosa Elisabeth Lauppe, Johan Liseth Hansen, Christian Gerdesköld, Mark H Rozenbaum, Anne Mette Strand, Merja Vakevainen, Johanna Kuusisto, Einar Gude, Finn Gustafsson, J Gustav Smith
Original research: Founder mutation in myosin-binding protein C with an early onset and a high penetrance in males (29 September, 2021)
Irene Méndez, Ana Isabel Fernández, Maria Ángeles Espinosa, Sofía Cuenca, Rebeca Lorca, José Fernando Rodríguez, Maria Tamargo, Marta García-Montero, Cristina Gómez, Silvia Vilches, Nélida Vázquez, Reyes Álvarez, Constancio Medrano, Raquel Yotti, Francisco Fernández-Avilés, Javier Bermejo
Original research: T2-weighted short-tau-inversion-recovery imaging reflects disease activity of cardiac sarcoidosis (28 September, 2021)
Reina Tonegawa-Kuji, Noriko Oyama-Manabe, Ryosuke Aoki, Shinya Nagayoshi, Christian Michael Hong Pawhay, Kengo Kusano, Takatomo Nakajima
Original research: Discrepancy between left ventricular hypertrophy by echocardiography and electrocardiographic hypertrophy: clinical characteristics and outcomes (23 September, 2021)
Yuta Seko, Takao Kato, Yuhei Yamaji, Yoshisumi Haruna, Eisaku Nakane, Tetsuya Haruna, Moriaki Inoko
Original research: Validation of the Intermountain Risk Score and Get with the Guidelines—Heart Failure Score in predicting mortality (23 August, 2021)
Erik K Engelsgjerd, Catherine P Benziger, Benjamin D Horne
Original research: Heart failure in pregnancy: what is the long-term impact of pregnancy on cardiac function? A tertiary care centre experience and systematic review (3 August, 2021)
Anudeep K Dodeja, Francesca Siegel, Katherine Dodd, Marwan Ma'ayeh, Laxmi S Mehta, Margaret M Fuchs, Kara M Rood, May Ling Mah, Elisa A Bradley

Interventional cardiology

Original research: Prevalence of iatrogenic atrial septal defects (iASD) after mitral valve (MV) transcatheter edge-to-edge repair (TEER) in the long-term follow-up (26 October, 2021)
Michael Paukovitsch, Leonhard Moritz Schneider, Christine Reichart, Nicoleta Nita, Wolfgang Rottbauer, Mirjam Keßler, Sinisa Markovic
Original research: Transcatheter aortic valve replacement using the iSleeve expandable sheath in small femoral arteries (12 October, 2021)
Natalie Glaser, Crochan J. O'Sullivan, Nawzad Saleh, Dinos Verouhis, Magnus Settergren, Rickard Linder, Andreas Rück
Original research: Predictors of clinical outcome following transcatheter aortic valve implantation: a prospective cohort study (23 September, 2021)
Lauren Dautzenberg, Judith E M Pals, Geert J Lefeber, Pieter R Stella, Masieh Abawi, Marielle Emmelot-Vonk, Huiberdina L Koek
Original research: Long-term outcomes after treatment of in-stent restenosis using the Absorb everolimus-eluting bioresorbable scaffold (13 September, 2021)
Mehdi Madanchi, Giacomo Maria Cioffi, Adrian Attinger-Toller, Mathias Wolfrum, Federico Moccetti, Thomas Seiler, Luca Vercelli, Philipp Burkart, Stefan Toggweiler, Richard Kobza, Matthias Bossard, Florim Cuculi
Original research: Is percutaneous coronary intervention safe during uninterrupted direct oral anticoagulant therapy in patients with atrial fibrillation and acute coronary syndromes? (14 July, 2021)
Leonardo De Luca, Andrea Rubboli, Leonardo Bolognese, Massimo Uguccioni, Donata Lucci, Simonetta Blengino, Jeness Campodonico, Ilaria Meynet, Silvia Maria Brach Prever, Andrea Di Lenarda, Domenico Gabrielli, Michele Massimo Gulizia

Pulmonary vascular disease

Original research: A pragmatic approach to risk assessment in pulmonary arterial hypertension using the 2015 European Society of Cardiology/European Respiratory Society guidelines (19 October, 2021)
Fabio Dardi, Alessandra Manes, Daniele Guarino, Elisa Zuffa, Alessandro De Lorenzis, Ilenia Magnani, Mariangela Rotunno, Alberto Ballerini, Gerardo Vito Lo Russo, Elena Nardi, Nazzareno Galiè, Massimiliano Palazzini
Original research: Characteristics and in-hospital outcomes of patients undergoing balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension: a time-trend analysis from the Japanese nationwide registry (14 September, 2021)
Shun Minatsuki, Mitsuyoshi Takahara, Arihiro Kiyosue, Satoshi Kodera, Masaru Hatano, Jiro Ando, Shun Kohsaka, Hideki Ishii, Toshiro Shinke, Tetsuya Amano, Yuji Ikari, Issei Komuro

Special populations

Original research: Cardiovascular safety profile of taxanes and vinca alkaloids: 30 years FDA registry experience (24 December, 2021)
Akshee Batra, Brijesh Patel, Daniel Addison, Lauren A Baldassarre, Nihar Desai, Neal Weintraub, Anita Deswal, Zeeshan Hussain, Sherry-Ann Brown, Sarju Ganatra, Vivek Agarwala, Purvish M Parikh, Michael Fradley, Arjun Ghosh, Avirup Guha
Original research: Soluble ST2 concentrations associate with in-hospital mortality and need for mechanical ventilation in unselected patients with COVID-19 (21 December, 2021)
Torbjorn Omland, Christian Prebensen, Christine Jonassen, My Svensson, Jan Erik Berdal, Ingebjørg Seljeflot, Peder Langeland Myhre
Original research: Prevalence of cardiac pathology and relation to mortality in a multiethnic population hospitalised with COVID-19 (15 November, 2021)
Gabriel Bioh, Christina Botrous, Emma Howard, Ashish Patel, Reinette Hampson, Roxy Senior
Original research: Normative blood pressure response to exercise stress testing in children and adolescents (18 October, 2021)
Melanie M Clarke, Diana Zannino, Natalie P Stewart, Jonathan P Glenning, Salvador Pineda-Guevara, Jolien Kik, Jonathan P Mynard, Michael M H Cheung
Original research: Combined anticoagulant and antiplatelet therapy is associated with an improved outcome in hospitalised patients with COVID-19: a propensity matched cohort study (5 October, 2021)
Kamal Matli, Nibal Chamoun, Aya Fares, Victor Zibara, Soad Al-Osta, Rabih Nasrallah, Pascale Salameh, Jacques Mokhbat, Georges Ghanem
Original research: Ventricular–vascular coupling is predictive of adverse clinical outcome in paediatric pulmonary arterial hypertension (28 September, 2021)
Melanie J Dufva, Dunbar Ivy, Kristen Campbell, Aimee Lam, Adam Rauff, Karel T N Breeman, Johannes M Douwes, Rolf M F Berger, Vitaly Oleg Kheyfets, Kendall Hunter
Original research: Echocardiography in suspected coronavirus infection: indications, limitations and impact on clinical management (10 August, 2021)
Megan M Sheehan, Yoshihito Saijo, Zoran B Popovic, Michael D Faulx
Original research: Protective lipid-lowering variants in healthy older individuals without coronary heart disease (2 August, 2021)
Paul Lacaze, Moeen Riaz, Robert Sebra, Amanda J Hooper, Jing Pang, Jane Tiller, Galina Polekhina, Andrew Tonkin, Chris Reid, Sophia Zoungas, Anne M Murray, Stephen Nicholls, Gerald Watts, Eric Schadt, John J McNeil

Valvular heart disease

Original research: Quality of life after transcatheter or surgical aortic valve replacement using the Toronto Aortic Stenosis Quality of Life Questionnaire (22 November, 2021)
Simon Kennon, Rima Styra, Nikolaos Bonaros, Lukas Stastny, Mauro Romano, Thierry Lefèvre, Carlo Di Mario, Pierluigi Stefàno, Flavio Luciano Ribichini, Dominique Himbert, Marina Urena-Alcazar, Jorge Salgado-Fernandez, Jose Joaquin Cuenca Castillo, Bruno Garcia, Cornelia Deutsch, Lenka Sykorova, Jana Kurucova, Martin Thoenes, Claudia Lüske, Peter Bramlage, Derk Frank
Original research: Predictors and clinical outcomes of poor symptomatic improvement after transcatheter aortic valve replacement (22 November, 2021)
Nobuhiro Yoshijima, Tetsuya Saito, Taku Inohara, Atsushi Anzai, Hikaru Tsuruta, Hideyuki Shimizu, Keiichi Fukuda, Toru Naganuma, Kazuki Mizutani, Masahiro Yamawaki, Norio Tada, Futoshi Yamanaka, Shinichi Shirai, Minoru Tabata, Hiroshi Ueno, Kensuke Takagi, Yusuke Watanabe, Masanori Yamamoto, Kentaro Hayashida
Original research: Escalating incidence of infective endocarditis in Europe in the 21st century (20 October, 2021)
Khawaja M Talha, Larry M Baddour, Martin H Thornhill, Verda Arshad, Wajeeha Tariq, Imad M Tleyjeh, Christopher G Scott, Meredith C Hyun, Kent R Bailey, Nandan S Anavekar, Raj Palraj, M Rizwan Sohail, Daniel C DeSimone, Mark J Dayer
Original research: Speckle tracking strain and ECG heterogeneity correlate in transcatheter aortic valve replacement-induced left bundle branch blocks and right ventricular paced rhythms (5 October, 2021)
Gordon M Burke, Bruna Araujo Silva, Alexandre A Marum, Alexandre L Bortolotto, Bruce D Nearing, Michael J Chen, Sarah Fostello, Jeffrey J Popma, Richard L Verrier, James D Chang
Original research: Low myocardial energetic efficiency is associated with increased mortality in aortic stenosis (23 August, 2021)
Edda Bahlmann, Eigir Einarsen, Dana Cramariuc, Helga Midtbø, Costantino Mancusi, Anne Rossebø, Stephan Willems, Eva Gerdts
Original research: Characteristics of infective endocarditis in a cancer population (3 August, 2021)
Cullen Grable, Syed W Yusuf, Juhee Song, George M Viola, Owais Ulhaq, Jose Banchs, Corey T Jensen, Harsh Goel, Saamir A Hassan
Original research: Early reduction of left atrial function predicts adverse clinical outcomes in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (7 July, 2021)
Jolanda Sabatino, Salvatore De Rosa, Isabella Leo, Antonio Strangio, Sabrina La Bella, Sabato Sorrentino, Annalisa Mongiardo, Carmen Spaccarotella, Alberto Polimeni, Ciro Indolfi

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FLOWER-MI and the root of the problem with non-culprit revascularisation (24 November, 2021)
Matthew E Li Kam Wa, Kalpa De Silva, Carlos Collet, Divaka Perera
Evaluation of low gradient severe aortic stenosis: should we change our outlook in the analysis of clinical data? (11 October, 2021)
Ivan Corazza, Margherita Zecchi, Romano Zannoli
Sex-based outcomes in contemporary antiplatelet therapy trials (28 July, 2021)
Mirvat Alasnag, Tara L Jones, Yasmin Hanfi, Nicola Ryan
Hiding unhealthy heart outcomes in a low-fat diet trial: the Women’s Health Initiative Randomized Controlled Dietary Modification Trial finds that postmenopausal women with established coronary heart disease were at increased risk of an adverse outcome if they consumed a low-fat ‘heart-healthy’ diet (21 July, 2021)
Timothy David Noakes
Ethical issues in two parallel trials of personalised criteria for implantation of implantable cardioverter defibrillators for primary prevention: the PROFID project—a position paper (14 July, 2021)
Dick Willems, Marieke Bak, Hanno Tan, Georg Lindinger, Ayca Kocar, Alireza Seperhi Shamloo, Georg Schmidt, Gerhard Hindricks, Nikolaos Dagres

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Table of contents

September 2021 - Volume 8 - 2

Editorial

Arrhythmias and sudden death

Aortic and vascular disease

Basic and translational research

Cardiac surgery

Cardiac risk factors and prevention

Coronary artery disease

Congenital heart disease

Health care delivery, economics and global health care

Heart failure and cardiomyopathies

Interventional cardiology

Pulmonary vascular disease

Special populations

Valvular heart disease

Viewpoint

Correction

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Table of contents

September 2021 - Volume 8 - 2

Editorial

Arrhythmias and sudden death

Aortic and vascular disease

Basic and translational research

Cardiac surgery

Cardiac risk factors and prevention

Coronary artery disease

Congenital heart disease

Health care delivery, economics and global health care

Heart failure and cardiomyopathies

Interventional cardiology

Pulmonary vascular disease

Special populations

Valvular heart disease

Viewpoint

Correction