Table 1.
Neutralization activities of antisera from SARS-CoV and COVID-19 patients.
| Patient serum | SARS-CoV S pseudovirion | SARS-CoV-2 S pseudovirion |
|---|---|---|
| SARS-CoV patient | >80 | 40 |
| COVID-19 patient #1 | Not detected | >80 |
| COVID-19 patient #2 | Not detected | 40 |
| COVID-19 patient #3 | Not detected | >80 |
| COVID-19 patient #4 | Not detected | >80 |
| COVID-19 patient #5 | Not detected | >80 |
SARS-CoV and SARS-CoV-2 S pseudovirions were pre-incubated with serially diluted patient sera for 1 h on ice, then virus-antibody mixture was added on 293/hACE2 cells. Cells were lysed 40 h later and pseudovirus transduction was measured. The highest dilution of the serum sample that decreased transduction by 50% or more was considered to be positive. Source data are provided as a Source Data file.