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Br J Cancer. 1975 Aug; 32(2): 193–198.
doi: 10.1038/bjc.1975.149
PMCID: PMC2024837
PMID: 764844
Reduced lethality in mice receiving a combined dose of cyclophosphamide and busulphan.
Abstract
Animals treated with a sufficiently high dose of busulphan die about 14 days later from bone marrow failure. A single, appropriately timed injection of cyclophosphamide can save these mice. The nature of this protection is shown to be the cyclophosphamide induced elaboration of a humoral factor which stimulates haemopoietic recovery.
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Selected References
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Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK