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Volume 15(20);  2023 Oct 31

Editorial

Poor communication between ER and mitochondria: a signature of ALS/FTD?
Christopher C.J. Miller, Patricia Gomez-Suaga
Aging (Albany NY) 2023 Oct 31; 15(20): 10814–10816. Published online 2023 Oct 20. doi: 10.18632/aging.205206
PMCID:
PMC10637802
Article PDF–322K

Research Perspective

Cholinergic centro-cingulate network in Parkinson disease and normal aging
Nicolaas I. Bohnen, Sygrid van der Zee, Roger Albin
Aging (Albany NY) 2023 Oct 31; 15(20): 10817–10820. Published online 2023 Oct 27. doi: 10.18632/aging.205209
PMCID:
PMC10637805
Abstract Article PDF–268K

Priority Research Paper

Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature
Shweta S. Dipali, Christina D. King, Jacob P. Rose, Joanna E. Burdette, Judith Campisi, Birgit Schilling, Francesca E. Duncan
Aging (Albany NY) 2023 Oct 31; 15(20): 10821–10855. Published online 2023 Oct 27. doi: 10.18632/aging.205190
PMCID:
PMC10637783
Abstract Article PDF–3.4M

Research Papers

Deciphering reproductive aging in women using a NOD/SCID mouse model for distinct physiological ovarian phenotypes
María Marchante, Noelia Ramirez-Martin, Anna Buigues, Jessica Martinez, Nuria Pellicer, Antonio Pellicer, Sonia Herraiz
Aging (Albany NY) 2023 Oct 31; 15(20): 10856–10874. Published online 2023 Oct 16. doi: 10.18632/aging.205086
PMCID:
PMC10637815
Abstract Article PDF–1.5M
Tissue immunoexpression of IL-6 and IL-18 in aging men with BPH and MetS and their relationship with lipid parameters and gut microbiota-derived short chain fatty acids
Weronika Ratajczak, Maria Laszczyńska, Aleksandra Rył, Barbara Dołęgowska, Olimpia Sipak, Ewa Stachowska, Marcin Słojewski, Anna Lubkowska
Aging (Albany NY) 2023 Oct 31; 15(20): 10875–10896. Published online 2023 Oct 16. doi: 10.18632/aging.205091
PMCID:
PMC10637784
Abstract Article PDF–1.6M
WNT enhancing signals in pancreatic cancer are transmitted by LGR6
Jing Wang, Dominik T. Koch, Felix O. Hofmann, Daniel Härtwig, Iris Beirith, Klaus Peter Janssen, Alexandr V. Bazhin, Hanno Niess, Jens Werner, Bernhard W. Renz, Matthias Ilmer
Aging (Albany NY) 2023 Oct 31; 15(20): 10897–10914. Published online 2023 Sep 27. doi: 10.18632/aging.205101
PMCID:
PMC10637827
Abstract Article PDF–1.4M
The Saccharomyces cerevisiae acetyltransferase Gcn5 exerts antagonistic pleiotropic effects on chronological ageing
Kaiqiang Li, Gabriele Mocciaro, Jules L. Griffin, Nianshu Zhang
Aging (Albany NY) 2023 Oct 31; 15(20): 10915–10937. Published online 2023 Oct 23. doi: 10.18632/aging.205109
PMCID:
PMC10637828
Abstract Article PDF–3.0M
Alcohol consumption and epigenetic age acceleration across human adulthood
Mengyao Wang, Yi Li, Meng Lai, Drew R. Nannini, Lifang Hou, Roby Joehanes, Tianxiao Huan, Daniel Levy, Jiantao Ma, Chunyu Liu
Aging (Albany NY) 2023 Oct 31; 15(20): 10938–10971. Published online 2023 Oct 26. doi: 10.18632/aging.205153
PMCID:
PMC10637803
Abstract Article PDF–2.2M
Chronic kidney disease causes blood-brain barrier breakdown via urea-activated matrix metalloproteinase-2 and insolubility of tau protein
Hisazumi Matsuki, Shintaro Mandai, Hiroki Shiwaku, Takaaki Koide, Naohiro Takahashi, Tomoki Yanagi, Shunsuke Inaba, Saaya Ida, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Eisei Sohara, Hidehiko Takahashi, Shinichi Uchida
Aging (Albany NY) 2023 Oct 31; 15(20): 10972–10995. Published online 2023 Oct 25. doi: 10.18632/aging.205164
PMCID:
PMC10637825
Abstract Article PDF–2.7M
BTN2A2, a new biomarker and therapeutic _target for glioma
Heping Wang, Shanrui Pu, Haitao Xu, Lihong Yang, Lishi Shao, Xi Chen, Xiaobin Huang, Jun Pu
Aging (Albany NY) 2023 Oct 31; 15(20): 10996–11011. Published online 2023 Oct 17. doi: 10.18632/aging.205039
PMCID:
PMC10637821
Abstract Article PDF–2.4M
A comprehensive prognostic and immunological analysis of telomere-related lncRNAs in kidney renal clear cell carcinoma
Ji Chen, Dong Zhang, Xiangbin Ren, Peng Wang
Aging (Albany NY) 2023 Oct 31; 15(20): 11012–11032. Published online 2023 Oct 16. doi: 10.18632/aging.205056
PMCID:
PMC10637817
Abstract Article PDF–2.9M
Dysregulated expression of slingshot protein phosphatase 1 (SSH1) disrupts circadian rhythm and WNT signaling associated to hepatocellular carcinoma pathogenesis
Shiue-Wei Lai, Yi-Chiao Cheng, Wen-Chien Huang, Vijesh Kumar Yadav, Iat-Hang Fong, Chi-Tai Yeh, Ching-Kuo Yang, Wei-Hwa Lee, Ming-Yao Chen
Aging (Albany NY) 2023 Oct 31; 15(20): 11033–11051. Published online 2023 Oct 13. doi: 10.18632/aging.205064
PMCID:
PMC10637823
Abstract Article PDF–2.1M
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma
Haitao Luo, Kai Huang, Mengqi Cheng, Xiaoyan Long, Xingen Zhu, Miaojing Wu
Aging (Albany NY) 2023 Oct 31; 15(20): 11052–11066. Published online 2023 Oct 17. doi: 10.18632/aging.205076
PMCID:
PMC10637790
Abstract Article PDF–1.8M
HLA-DPA1 overexpression inhibits cancer progression, reduces resistance to cisplatin, and correlates with increased immune infiltration in lung adenocarcinoma
Ke Shi, Qian-Yun Li, Yun-Qiang Zhang, Huan Huang, Dong-Xiao Ding, Wei-Min Luo, Jun Zhang, Qiang Guo
Aging (Albany NY) 2023 Oct 31; 15(20): 11067–11091. Published online 2023 Oct 27. doi: 10.18632/aging.205082
PMCID:
PMC10637812
Abstract Article PDF–3.8M
Identification and validation of a cancer-associated fibroblasts-related scoring system to predict prognosis and immune landscape in hepatocellular carcinoma through integrated analysis of single-cell and bulk RNA-sequencing
Lingling Bao, Xuede Zhang, Wenjuan Wang, Bitao Jiang
Aging (Albany NY) 2023 Oct 31; 15(20): 11092–11113. Published online 2023 Oct 18. doi: 10.18632/aging.205099
PMCID:
PMC10637792
Abstract Article PDF–3.6M
Naked cuticle homolog 1 prevents mouse pulmonary arterial hypertension via inhibition of Wnt/β-catenin and oxidative stress
Shanwu Wei, Lu Lin, Wen Jiang, Jie Chen, Gu Gong, Daming Sui
Aging (Albany NY) 2023 Oct 31; 15(20): 11114–11130. Published online 2023 Oct 18. doi: 10.18632/aging.205105
PMCID:
PMC10637826
Abstract Article PDF–1.6M
Triptolide inhibits epithelial ovarian tumor growth by blocking the hedgehog/Gli pathway
Lanyan Hu, Mai Gao, Huifu Jiang, Lingling Zhuang, Ying Jiang, Siqi Xie, Hong Zhang, Qian Wang, Qi Chen
Aging (Albany NY) 2023 Oct 31; 15(20): 11131–11151. Published online 2023 Oct 17. doi: 10.18632/aging.205110
PMCID:
PMC10637820
Abstract Article PDF–2.9M
The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway
Jing Xu, Peng Chen, Dongzhi Wu, Qiang Zhou, Sijie Chen, Xiang Ding, Hongping Xiong
Aging (Albany NY) 2023 Oct 31; 15(20): 11152–11161. Published online 2023 Oct 17. doi: 10.18632/aging.205118
PMCID:
PMC10637786
Abstract Article PDF–1.6M
Machine learning developed a PI3K/Akt pathway-related signature for predicting prognosis and drug sensitivity in ovarian cancer
Xiaofang Han, Liu Yang, Hui Tian, Yuanyuan Ji
Aging (Albany NY) 2023 Oct 31; 15(20): 11162–11183. Published online 2023 Oct 17. doi: 10.18632/aging.205119
PMCID:
PMC10637788
Abstract Article PDF–5.1M
Inhibiting microRNA-200a-3p attenuates pyroptosis via _targeting the SIRT1/NF-κB/NLRP3 pathway in H2O2-induced HAEC
Jia Liu, Youyou Yan, Dongdong Zheng, Jifeng Zhang, Junnan Wang
Aging (Albany NY) 2023 Oct 31; 15(20): 11184–11200. Published online 2023 Oct 23. doi: 10.18632/aging.205121
PMCID:
PMC10637806
Abstract Article PDF–2.2M
Tryptophan metabolism-related gene expression patterns: unveiling prognostic insights and immune landscapes in uveal melanoma
Jing Wang, Tienan Zhao, Bo Li, Wei Wei
Aging (Albany NY) 2023 Oct 31; 15(20): 11201–11216. Published online 2023 Oct 13. doi: 10.18632/aging.205122
PMCID:
PMC10637787
Abstract Article PDF–1.8M
Identification of cellular senescence-related signature for predicting prognosis and therapeutic response of acute myeloid leukemia
Fangmin Zhong, Yulin Yang, Fangyi Yao, Jing Liu, Xiajing Yu, Xin-Lu Wang, Bo Huang, Xiao-Zhong Wang
Aging (Albany NY) 2023 Oct 31; 15(20): 11217–11226. Published online 2023 Oct 13. doi: 10.18632/aging.205123
PMCID:
PMC10637797
Abstract Article PDF–1.5M
Electroacupuncture pretreatment protects against anesthesia/surgery-induced cognitive decline by activating CREB via the ERK/MAPK pathway in the hippocampal CA1 region in aged rats
Hongjie Huang, Yanan Li, Xupeng Wang, Qi Zhang, Juan Zhao, Qiujun Wang
Aging (Albany NY) 2023 Oct 31; 15(20): 11227–11243. Published online 2023 Oct 19. doi: 10.18632/aging.205124
PMCID:
PMC10637818
Abstract Article PDF–1.7M
CDKN2A was a cuproptosis-related gene in regulating chemotherapy resistance by the MAGE-A family in breast cancer: based on artificial intelligence (AI)-constructed pan-cancer risk model
Hong Wan, Xiaowei Yang, Guopeng Sang, Zhifan Ruan, Zichen Ling, Mingzhao Zhang, Chang Liu, Xiangyang Hu, Tao Guo, Juntong He, Defeng Liu, Jing Pei
Aging (Albany NY) 2023 Oct 31; 15(20): 11244–11267. Published online 2023 Oct 19. doi: 10.18632/aging.205125
PMCID:
PMC10637804
Abstract Article PDF–3.6M
Integrated bulk and scRNA sequence identified anoikis-related diagnostic biomarkers and potential association with immune infiltration in type A aortic dissection
Kexiang Feng, Zhongwei Zhang, Jie Luo, Wenjie Wang, Tianjie Li, Jing Luo, Hongbo Huang
Aging (Albany NY) 2023 Oct 31; 15(20): 11268–11285. Published online 2023 Oct 24. doi: 10.18632/aging.205126
PMCID:
PMC10637813
Abstract Article PDF–3.6M
STK4 is a prognostic biomarker correlated with immune infiltrates in clear cell renal cell carcinoma
Zi-Yuan Bai, Lu-Shan Peng, Run-Qi Li, Xianchu Peng, Zhe Yang
Aging (Albany NY) 2023 Oct 31; 15(20): 11286–11297. Published online 2023 Oct 20. doi: 10.18632/aging.205127
PMCID:
PMC10637789
Abstract Article PDF–1.6M
Single-cell landscape and spatial transcriptomic analysis reveals macrophage infiltration and glycolytic metabolism in kidney renal clear cell carcinoma
Chen-Yueh Wen, Jui-Hu Hsiao, Yen-Dun Tony Tzeng, Renin Chang, Yi-Ling Tsang, Chen-Hsin Kuo, Chia-Jung Li
Aging (Albany NY) 2023 Oct 31; 15(20): 11298–11312. Published online 2023 Oct 16. doi: 10.18632/aging.205128
PMCID:
PMC10637799
Abstract Article PDF–2.4M
Role of NF-κB pathway in kidney renal clear cell carcinoma and its potential therapeutic implications
Jiaao Sun, Feng Chen, Guangzhen Wu
Aging (Albany NY) 2023 Oct 31; 15(20): 11313–11330. Published online 2023 Oct 16. doi: 10.18632/aging.205129
PMCID:
PMC10637793
Abstract Article PDF–2.3M
Exosome and lipid metabolism-related genes in pancreatic adenocarcinoma: a prognosis analysis
Jia Wu, Yajun Li, Ghulam Nabi, Xin Huang, Xu Zhang, Yuanzhen Wang, Liya Huang
Aging (Albany NY) 2023 Oct 31; 15(20): 11331–11368. Published online 2023 Oct 18. doi: 10.18632/aging.205130
PMCID:
PMC10637811
Abstract Article PDF–6.2M
Comprehensive analysis of integrin αvβ3/α6β1 in prognosis and immune escape of prostate cancer
Yang Liu, Jia-Xin He, Bo Ji, Jin-Feng Wang, Lu Zhang, Zhong-Qi Pang, Jian-She Wang, Bei-Chen Ding, Ming-Hua Ren
Aging (Albany NY) 2023 Oct 31; 15(20): 11369–11388. Published online 2023 Oct 19. doi: 10.18632/aging.205131
PMCID:
PMC10637796
Abstract Article PDF–4.0M
Development of an immunogenic cell death prognostic signature for predicting clinical outcome and immune infiltration characterization in stomach adenocarcinoma
Ye Liu, Lijia Zhang, Xue Lei, Xinyu Yin, Songjiang Liu
Aging (Albany NY) 2023 Oct 31; 15(20): 11389–11411. Published online 2023 Oct 19. doi: 10.18632/aging.205132
PMCID:
PMC10637829
Abstract Article PDF–4.7M
Molecular characterization of ferroptosis in soft tissue sarcoma constructs a prognostic and immunotherapeutic signature through experimental and bioinformatics analyses
Zhi-Qiang Yang, Liang-Yu Guo, Kang-Wen Xiao, Chong Zhang, Min-Hao Wu, Fei-Fei Yan, Lin Cai
Aging (Albany NY) 2023 Oct 31; 15(20): 11412–11447. Published online 2023 Oct 20. doi: 10.18632/aging.205133
PMCID:
PMC10637810
Abstract Article PDF–4.4M
PPIH gene regulation system and its prognostic significance in hepatocellular carcinoma: a comprehensive analysis
Jun Ye, Yilin Pang, Xunjun Yang, Chuan Zhang, Lei Shi, Zhitao Chen, Guijia Huang, Xianhe Wang, Fangyang Lu
Aging (Albany NY) 2023 Oct 31; 15(20): 11448–11470. Published online 2023 Oct 23. doi: 10.18632/aging.205134
PMCID:
PMC10637785
Abstract Article PDF–2.6M
The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study
Yuanqing Cai, Huijun Sun, Xingyu Song, Jianyu Zhao, Dong Xu, Mozhen Liu
Aging (Albany NY) 2023 Oct 31; 15(20): 11471–11488. Published online 2023 Oct 19. doi: 10.18632/aging.205136
PMCID:
PMC10637795
Abstract Article PDF–2.6M
Anti-cancer _targets and molecular mechanisms of formononetin in treating osteosarcoma based on network pharmacology
Lizhi Chen, Yue Zhou, Zheng Weng, Shuang Liu, Ting Li, Yanfang Wang, Yang Yang, Hongmei Liu, Wenhua Huang
Aging (Albany NY) 2023 Oct 31; 15(20): 11489–11507. Published online 2023 Oct 20. doi: 10.18632/aging.205139
PMCID:
PMC10637808
Abstract Article PDF–2.3M
Single-cell analysis reveals exosome-associated biomarkers for prognostic prediction and immunotherapy in lung adenocarcinoma
Shengrong Lin, Shengjie Zhou, Xin Han, Yang Yang, Hao Zhou, Xuejiao Chang, Yefeng Zhou, Yuqin Ding, Huihui Lin, Qing Hu
Aging (Albany NY) 2023 Oct 31; 15(20): 11508–11531. Published online 2023 Oct 24. doi: 10.18632/aging.205140
PMCID:
PMC10637798
Abstract Article PDF–5.3M
Indoxyl sulfate induced frailty in patients with end-stage renal disease by disrupting the PGC-1α–FNDC5 axis
Yi-Chou Hou, Min-Tser Liao, Kuo-Wang Tsai, Cai-Mei Zheng, Hui-Wen Chiu, Kuo-Cheng Lu
Aging (Albany NY) 2023 Oct 31; 15(20): 11532–11545. Published online 2023 Oct 23. doi: 10.18632/aging.205141
PMCID:
PMC10637807
Abstract Article PDF–1.2M
Icariin improves cognitive impairment by inhibiting ferroptosis of nerve cells
Yang Yang, Yiming Fu, Zhipeng Qin, Hongyan Pei, Liping Zhai, Qiaobing Guan, Shasha Wu, Heping Shen
Aging (Albany NY) 2023 Oct 31; 15(20): 11546–11553. Published online 2023 Oct 24. doi: 10.18632/aging.205144
PMCID:
PMC10637794
Abstract Article PDF–1.0M
Comprehensive analysis of transcriptome data and experimental identification show that solute carrier 35 member A2 (SLC35A2) is a prognostic marker of colorectal cancer
Yue Wang, Liang Chen, Jing Chen, Zhenzhen Bai, Liyu Cao
Aging (Albany NY) 2023 Oct 31; 15(20): 11554–11570. Published online 2023 Oct 26. doi: 10.18632/aging.205145
PMCID:
PMC10637800
Abstract Article PDF–2.0M
Metabolic and senescence characteristics associated with the immune microenvironment in non-small cell lung cancer: insights from single-cell RNA sequencing
Hongliang Liao, Zihao Wan, Yaqin Liang, Lin Kang, Renping Wan
Aging (Albany NY) 2023 Oct 31; 15(20): 11571–11587. Published online 2023 Oct 26. doi: 10.18632/aging.205146
PMCID:
PMC10637824
Abstract Article PDF–2.1M
Immunobiological signatures and the emerging role of SPP1 in predicting tumor heterogeneity, malignancy, and clinical outcomes in stomach adenocarcinoma
Yanan Wu, Lingyu Ren, Yichun Tang, Zhu Zhu, Shifan Liu, Yan Jiang, Siming Zhang, Xiaocan Zhuang, Yuanbiao Chen
Aging (Albany NY) 2023 Oct 31; 15(20): 11588–11610. Published online 2023 Oct 26. doi: 10.18632/aging.205148
PMCID:
PMC10637809
Abstract Article PDF–3.5M
BCL2A1 is associated with tumor-associated macrophages and unfavorable prognosis in human gliomas
Lun Gao, Zhang Ye, Shu Peng, Pan Lei, Ping Song, Zhiyang Li, Long Zhou, Qiuwei Hua, Li Cheng, Hangyu Wei, Junhui Liu, Qiang Cai
Aging (Albany NY) 2023 Oct 31; 15(20): 11611–11638. Published online 2023 Oct 25. doi: 10.18632/aging.205149
PMCID:
PMC10637801
Abstract Article PDF–3.9M
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway
Huihong Li, Caiyun Zhang, Yangjie Zhou, Yunfei Deng, Xiaoqing Zheng, Xiehua Xue
Aging (Albany NY) 2023 Oct 31; 15(20): 11639–11653. Published online 2023 Oct 26. doi: 10.18632/aging.205151
PMCID:
PMC10637819
Abstract Article PDF–1.3M
PCMT1 regulates the migration, invasion, and apoptosis of prostate cancer through modulating the PI3K/AKT/GSK-3β pathway
Jiacheng Zhong, Chao Yuan, Lin Liu, Yang Du, Yumin Hui, Zhiyuan Chen, Changhui Diao, Rui Yang, Guiyong Liu, Xiuheng Liu
Aging (Albany NY) 2023 Oct 31; 15(20): 11654–11671. Published online 2023 Oct 27. doi: 10.18632/aging.205152
PMCID:
PMC10637816
Abstract Article PDF–2.0M
Identification of key circadian rhythm genes in skin aging based on bioinformatics and machine learning
Xiao Xiao, Hao Feng, Yangying Liao, Hua Tang, Lan Li, Ke Li, Feng Hu
Aging (Albany NY) 2023 Oct 31; 15(20): 11672–11689. Published online 2023 Oct 30. doi: 10.18632/aging.205155
PMCID:
PMC10637791
Abstract Article PDF–2.9M

Corrections

Correction for: ASXL1 promotes adrenocortical carcinoma and is associated with chemoresistance to EDP regimen
Liang Wang, Yinfeng Lyu, Yuqing Li, Kunping Li, Hui Wen, Chenchen Feng, Ning Li
Aging (Albany NY) 2023 Oct 31; 15(20): 11690–11691. Published online 2023 Oct 30. doi: 10.18632/aging.205255
Corrects:
Aging (Albany NY). 2021 Sep 30; 13(18): 22286–22297.
PMCID:
PMC10637814
Correction PDF–1.1M
Correction for: miR-320 accelerates chronic heart failure with cardiac fibrosis through activation of the IL6/STAT3 axis
Fang Li, Shan-Shan Li, Hui Chen, Jian-Zhi Zhao, Jie Hao, Jin-Ming Liu, Xiu-Guang Zu, Wei Cui
Aging (Albany NY) 2023 Oct 31; 15(20): 11692–11693. Published online 2023 Oct 30. doi: 10.18632/aging.205256
Corrects:
Aging (Albany NY). 2021 Sep 30; 13(18): 22516–22527.
PMCID:
PMC10637822
Correction PDF–512K
Articles from Aging (Albany NY) are provided here courtesy of Impact Journals, LLC
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