Review
doi: 10.1016/s0952-7915(01)00304-1.
Toll-like receptors: key mediators of microbe detection
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- PMID: 11790539
- DOI: 10.1016/s0952-7915(01)00304-1
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Review
Toll-like receptors: key mediators of microbe detection
Curr Opin Immunol.
2002 Feb.
Abstract
Toll-like receptors are pattern-recognition receptors that have key roles in detecting microbes and initiating inflammatory responses. Recently, a host of new microbial products that activate specific Toll-like receptors have been defined, and additional components that mediate intracellular signaling have been identified. There has also been greater recognition of the importance of specific Toll-like receptors in host defense.
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