doi: 10.1002/prot.10390.
A protein-protein docking benchmark
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- PMID: 12784372
- DOI: 10.1002/prot.10390
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A protein-protein docking benchmark
Proteins.
.
Abstract
We have developed a nonredundant benchmark for testing protein-protein docking algorithms. Currently it contains 59 test cases: 22 enzyme-inhibitor complexes, 19 antibody-antigen complexes, 11 other complexes, and 7 difficult test cases. Thirty-one of the test cases, for which the unbound structures of both the receptor and ligand are available, are classified as follows: 16 enzyme-inhibitor, 5 antibody-antigen, 5 others, and 5 difficult. Such a centralized resource should benefit the docking community not only as a large curated test set but also as a common ground for comparing different algorithms. The benchmark is available at (http://zlab.bu.edu/~rong/dock/benchmark.shtml).
Copyright 2003 Wiley-Liss, Inc.
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