doi: 10.1016/s0960-894x(03)00798-4.
Glucose-lowering in a db/db mouse model by dihydropyridine diacid glycogen phosphorylase inhibitors
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- PMID: 14505637
- DOI: 10.1016/s0960-894x(03)00798-4
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Glucose-lowering in a db/db mouse model by dihydropyridine diacid glycogen phosphorylase inhibitors
Bioorg Med Chem Lett.
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Abstract
The synthesis of a series of novel dihdyropyridine diacid glycogen phosphorylase inhibitors is presented. SAR and functional assay data are discussed, along with the effect of a single inhibitor on blood glucose in a diabetic animal model.
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