Influence of carteolol and timolol on IOP an visual fields in glaucoma: a multi-center, double-masked, prospective study
- PMID: 1490088
- DOI: 10.1177/112067219200200402
Influence of carteolol and timolol on IOP an visual fields in glaucoma: a multi-center, double-masked, prospective study
Abstract
The influences of Carteolol and Timolol eye drops on intraocular pressure (IOP) and visual fields were compared in a multi-center, double-masked, prospective study. Two-hundred and forty eyes of 120 patients were initially included in the study, and 142 eyes of 72 patients fulfilled all the criteria for final statistical analysis. Both drugs significantly reduced IOP. The visual fields in both treatment groups did not change during one year of treatment. In both groups some patients improved slightly, and others deteriorated slightly. This indicates that locally applied beta-blockers may efficiently stop further progression of visual field defects in cases with increased IOP and early visual field damage. There was no difference between Carteolol and Timolol in this regard. The side effects were minimal, and there were no differences in their frequency or intensity in the two treatment groups.
Similar articles
-
Comparison of the effects of 0.5% timolol maleate, 2% carteolol hydrochloride, and 0.3% metipranolol on intraocular pressure and perimetry findings and evaluation of their ocular and systemic effects.J Glaucoma. 2000 Feb;9(1):45-50. doi: 10.1097/00061198-200002000-00009. J Glaucoma. 2000. PMID: 10708231 Clinical Trial.
-
Central nervous system and plasma lipid profiles associated with carteolol and timolol in postmenopausal black women.J Glaucoma. 1999 Dec;8(6):388-95. J Glaucoma. 1999. PMID: 10604299 Clinical Trial.
-
A 7 year prospective comparative study of three topical beta blockers in the management of primary open angle glaucoma.Br J Ophthalmol. 2001 Aug;85(8):962-8. doi: 10.1136/bjo.85.8.962. Br J Ophthalmol. 2001. PMID: 11466256 Free PMC article. Clinical Trial.
-
Effects of dorzolamide 2% added to timolol maleate 0.5% on intraocular pressure, retrobulbar blood flow, and the progression of visual field damage in patients with primary open-angle glaucoma: a single-center, 4-year, open-label study.Clin Ther. 2008 Jun;30(6):1120-34. doi: 10.1016/j.clinthera.2008.06.006. Clin Ther. 2008. PMID: 18640468 Clinical Trial.
-
A 3-month comparison of 1% and 2% carteolol and 0.5% timolol in open-angle glaucoma.Graefes Arch Clin Exp Ophthalmol. 1991;229(3):258-61. doi: 10.1007/BF00167880. Graefes Arch Clin Exp Ophthalmol. 1991. PMID: 1869063 Clinical Trial.
Cited by
-
The discovery of the Flammer syndrome: a historical and personal perspective.EPMA J. 2017 May 22;8(2):75-97. doi: 10.1007/s13167-017-0090-x. eCollection 2017 Jun. EPMA J. 2017. PMID: 28725290 Free PMC article. Review.
-
Ocular carteolol: a review of its use in the management of glaucoma and ocular hypertension.Drugs Aging. 2007;24(6):509-28. doi: 10.2165/00002512-200724060-00007. Drugs Aging. 2007. PMID: 17571916 Review.
-
Medical interventions for primary open angle glaucoma and ocular hypertension.Cochrane Database Syst Rev. 2007 Oct 17;2007(4):CD003167. doi: 10.1002/14651858.CD003167.pub3. Cochrane Database Syst Rev. 2007. PMID: 17943780 Free PMC article. Review.
-
Ocular hypotensive efficacy and safety of once daily carteolol alginate.Br J Ophthalmol. 2001 Aug;85(8):921-4. doi: 10.1136/bjo.85.8.921. Br J Ophthalmol. 2001. PMID: 11466245 Free PMC article. Clinical Trial.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
