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Review
. 2004 Feb 4;43(3):317-27.
doi: 10.1016/j.jacc.2003.07.046.

Heart failure with preserved left ventricular systolic function; epidemiology, clinical characteristics, and prognosis

Karen Hogg  1 , Karl Swedberg, John McMurray
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Free article
Review

Heart failure with preserved left ventricular systolic function; epidemiology, clinical characteristics, and prognosis

Karen Hogg et al. J Am Coll Cardiol. .
Free article

Abstract

Recent cross-sectional, population-based echocardiographic studies show that about half of all patients with heart failure have preserved left ventricular systolic function (HF-PSF). Cohort studies of hospitalized patients show a smaller proportion of HF-PSF. Compared to those with reduced systolic function, patients with HF-PSF are more often female, older, less likely to have coronary artery disease, and more likely to have hypertension. Patients with HF-PSF are less symptomatic and receive different pharmacologic therapy than patients with reduced systolic function. Morbidity and mortality rates in patients with HF-PSF are high but not quite as high as in patients with reduced systolic function. Though much has recently been learned about the syndrome of HF-PSF, many questions remain to be answered, not least how it should be treated.

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