Complex malformations of the female genital tract. New types and revision of classification
- PMID: 15333604
- DOI: 10.1093/humrep/deh423
Complex malformations of the female genital tract. New types and revision of classification
Abstract
Background: Complex malformations of the female genital tract are often incorrectly identified, treated and reported, probably due to not considering the malformation as a cause of the clinical symptoms and neither the embryological origin of the different elements of the genitourinary tract.
Methods: Complex malformations are studied and classified, and new types are presented. The new types of complex malformations presented are: (i) Cases of unilateral vaginal or cervico-vaginal atresia with renal agenesis and uterine duplication, with or without communication between hemiuteri; (ii) the unilateral Rokitansky syndrome; and (iii) the combination in the same patient of unilateral Rokitansky syndrome (Müllerian defect) on one side and blind vagina and ipsilateral renal agenesis syndrome (Wolffian defect) on the other side.
Results: A revised version of the clinical and embryological classification of genital malformations is presented and an associated diagram points out the origin of these malformations.
Conclusions: These genital malformative anomalies reaffirm our hypothesis about the embryology of the human vagina as deriving from the Wolffian ducts and the Müllerian tubercle; and they show that gynecologists should be aware of the related symptoms and the embryology of the female genital tract in order to achieve a better comprehension of the malformations for their right correction or therapeutic approach.
Similar articles
-
Unilateral renal agenesis and female genital tract pathologies.Acta Obstet Gynecol Scand. 2010 Nov;89(11):1424-31. doi: 10.3109/00016349.2010.512067. Epub 2010 Aug 30. Acta Obstet Gynecol Scand. 2010. PMID: 20799917
-
The presentation and management of complex female genital malformations.Hum Reprod Update. 2016 Jan-Feb;22(1):48-69. doi: 10.1093/humupd/dmv048. Epub 2015 Nov 3. Hum Reprod Update. 2016. PMID: 26537987 Review.
-
Experimental contributions to the study of the embryology of the vagina.Hum Reprod. 2006 Jun;21(6):1623-8. doi: 10.1093/humrep/del031. Epub 2006 Feb 13. Hum Reprod. 2006. PMID: 16476676
-
Clinical aspects of Mayer-Rokitansky-Kuester-Hauser syndrome: recommendations for clinical diagnosis and staging.Hum Reprod. 2006 Mar;21(3):792-7. doi: 10.1093/humrep/dei381. Epub 2005 Nov 10. Hum Reprod. 2006. PMID: 16284062
-
Embryological observations on the female genital tract.Hum Reprod. 1992 Apr;7(4):437-45. doi: 10.1093/oxfordjournals.humrep.a137666. Hum Reprod. 1992. PMID: 1522183 Review.
Cited by
-
A new magnetic resonance imaging-based PUMCH classification system for congenital cervical malformations: devising a standardised diagnosis pathway.Insights Imaging. 2024 Jul 18;15(1):177. doi: 10.1186/s13244-024-01708-6. Insights Imaging. 2024. PMID: 39020237 Free PMC article.
-
Incidental diagnosis of unilateral renal and adnexal agenesis in a 46-year-old multiparous woman.Am J Case Rep. 2013 Jul 8;14:238-40. doi: 10.12659/AJCR.883970. Print 2013. Am J Case Rep. 2013. PMID: 23847711 Free PMC article.
-
Atypical presentation of obstructed hemivagina and ipsilateral renal anomaly.Urol Case Rep. 2018 May 18;19:70-71. doi: 10.1016/j.eucr.2018.05.011. eCollection 2018 Jul. Urol Case Rep. 2018. PMID: 29888199 Free PMC article. No abstract available.
-
Müllerian Anomalies Prevalence Diagnosed by Hysteroscopy and Laparoscopy in Mexican Infertile Women: Results from a Cohort Study.Diagnostics (Basel). 2019 Oct 17;9(4):149. doi: 10.3390/diagnostics9040149. Diagnostics (Basel). 2019. PMID: 31627332 Free PMC article.
-
Mayer-Rokitansky-Kuster-Hauser syndrome: a review.Int J Womens Health. 2015 Nov 2;7:865-70. doi: 10.2147/IJWH.S75637. eCollection 2015. Int J Womens Health. 2015. PMID: 26586965 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
