Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Aug;18(4):442-5.
doi: 10.1053/j.jvca.2004.05.021.

The incidence and risk of acute renal failure after cardiac surgery

Tiziana Bove  1 , Maria Grazia Calabrò, Giovanni Landoni, Giacomo Aletti, Giovanni Marino, Giuseppe Crescenzi, Concetta Rosica, Alberto Zangrillo
Affiliations

The incidence and risk of acute renal failure after cardiac surgery

Tiziana Bove et al. J Cardiothorac Vasc Anesth. 2004 Aug.

Abstract

Objective: To evaluate outcome and risk factors of acute renal failure in a surgical population with or without preoperative renal dysfunction.

Design: Observational study.

Setting: Intensive care unit at a University Hospital.

Participants: Five thousand sixty-eight consecutive adult patients who underwent cardiac surgery with cardiopulmonary bypass.

Interventions: Perioperative variables measured were age, sex, basic pathology, preoperative renal impairment defined as creatinine >1.4 mg/dL, ventricular dysfunction, preoperative neurologic event, chronic obstructive pulmonary disease, diabetes, type of surgery, use of intra-aortic balloon pump (IABP), cardiopulmonary bypass (CPB) duration, redo or emergency surgery, hemorrhage, blood transfusion, surgical revisions, and postoperative complications.

Measurements and main results: Acute renal failure (100% creatinine increase) developed in 171 (3.4%) patients, whereas 94 patients (1.9% of the population) had renal replacement therapy. Hospital mortality was 40.9% in patients with acute renal failure and increased to 63.8% when renal replacement therapy was requested. Sex, age, emergency surgery, low ejection fraction, IABP device, redo, diabetes, mitral valve surgery, CPB duration, and preoperative renal disease were independently associated with acute renal failure at a multivariate analysis.

Conclusion: This study confirms that acute renal failure is one of the major complications of cardiac surgery, identifies the risk factors, and suggests that optimizing cardiac output and reducing CPB time could improve the outcome of patients at high risk of acute renal failure.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

LinkOut - more resources

  NODES
twitter 2