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. 2005 Mar 22;6(1):13.
doi: 10.1186/1471-2296-6-13.

Trends in the prevalence and management of diagnosed type 2 diabetes 1994-2001 in England and Wales

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Trends in the prevalence and management of diagnosed type 2 diabetes 1994-2001 in England and Wales

Simon Lusignan et al. BMC Fam Pract. .

Abstract

Background: Type 2 diabetes is an important cause of morbidity and mortality. Its prevalence appears to be increasing. Guidelines exist regarding its management. Recommendations regarding drug therapy have changed. Little is known about the influence of these guidelines and changed recommendations on the actual management of patients with type 2 diabetes. This study aims to document trends in the prevalence, drug treatment and recording of measures related to the management of type 2 diabetes; and to assess whether recommended _targets can be met.

Methods: The population comprised subjects registered between 1994 and 2001 with 74 general practices in England and Wales which routinely contribute to the Doctors' Independent Network database. Approximately 500,000 patients and 10,000 type 2 diabetics were registered in each year.

Results: Type 2 diabetes prevalence rose from 17/1000 in 1994 to 25/1000 in 2001. Drug therapy has changed: use of long acting sulphonylureas is falling while that of short acting sulphonylureas, metformin and newer therapies including glitazones is increasing. Electronic recording of HbA1c, blood pressure, cholesterol and weight have risen steadily, and improvements in control of blood pressure and cholesterol levels have occurred. However, glycaemic control has not improved, and obesity has increased. The percentage with a BMI under 25 kg/m2 fell from 27.0% in 1994 to 19.4% in 2001 (p < 0.001).

Conclusion: Prevalence of type 2 diabetes is increasing. Its primary care management has changed in accordance with best evidence. Monitoring has improved, but further improvement is possible. Despite this, glycaemic control has not improved, while the prevalence of obesity in the diabetic population is rising.

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Figures

Figure 3
Figure 3
Distribution of the practice percentage of diabetics with a risk factor measured by year. – Boxes indicate the median, lower and upper quartiles Whiskers extend to the practice immediately proceeding 1.5 times the interquartile range from the median. Practices lying outside this range are individually plotted. – % of all measurements that were numeric and valid were for each risk factor: BMI (95%), Blood Pressure (97%), HbA1c (61%) and Cholesterol (91%).
Figure 1
Figure 1
Prevalence of type 2 diabetic treatment groups in the DIN database over time. Blue – On insulin, Red – On oral drug only, Green – Diet controlled only
Figure 2
Figure 2
Changes in the non-insulin treatment of type 2 diabetics over time. Light Blue – Metformin, Red – Short acting sulphonylurea, Green – Long acting acting sulphonylurea, Orange – Ultra long acting sulphonylurea, Purple – Acarbose, Yellow – Meglitinides, Dark Blue – Thiazolidinediones/Glitazones Footnote: Treatment groups are not mutually exclusive
Figure 4
Figure 4
(NICE/NSF) Risk factor _targets achieved in all type 2 diabetics by year. (Results are age & sex standardised to the 2001 population) Denominators are the number of subjects with a valid numerical value recorded. HbA1C results start in 1997 as numerical codes could not be recorded prior to 1997.

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