Review
doi: 10.1016/j.clindermatol.2004.07.023.
Engineered skin substitutes: practices and potentials
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- PMID: 16023936
- DOI: 10.1016/j.clindermatol.2004.07.023
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Review
Engineered skin substitutes: practices and potentials
Clin Dermatol.
2005 Jul-Aug.
Abstract
Wound healing can be problematic in several clinical settings because of massive tissue injury (burns), wound healing deficiencies (chronic wounds), or congenital conditions and diseases. Engineered skin substitutes have been developed to address the medical need for wound coverage and tissue repair. Currently, no engineered skin substitute can replace all of the functions of intact human skin. A variety of biologic dressings and skin substitutes have however contributed to improved outcomes for patients suffering from acute and chronic wounds. These include acellular biomaterials and composite cultured skin analogs containing allogeneic or autologous cultured skin cells.
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