Review
doi: 10.1016/j.cub.2005.08.002.
RNA turnover: unexpected consequences of being tailed
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- PMID: 16111937
- DOI: 10.1016/j.cub.2005.08.002
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Review
RNA turnover: unexpected consequences of being tailed
Curr Biol.
.
Free article
Abstract
In eukaryotic cells, the 3' poly(A) tails found on mRNA influence their stability and translation. The discovery of a second nuclear poly(A) polymerase complex has fueled a series of reports defining a new and unexpected role for 3' end poly(A) tails in the nuclear surveillance and turnover of noncoding RNAs and intergenic mRNAs of unknown function.
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