Mitochondrial dynamics and Ca2+ signaling
- PMID: 16750865
- DOI: 10.1016/j.bbamcr.2006.04.002
Mitochondrial dynamics and Ca2+ signaling
Abstract
Recent data shed light on two novel aspects of the mitochondria-Ca2+ liaison. First, it was extensively investigated how Ca2+ handling is controlled by mitochondrial shape, and positioning; a playground also of cell death and survival regulation. On the other hand, significant progress has been made to explore how intra- and near-mitochondrial Ca2+ signals modify mitochondrial morphology and cellular distribution. Here, we shortly summarize these advances and provide a model of Ca2+-mitochondria interactions.
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