GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
- PMID: 18436948
- PMCID: PMC2335261
- DOI: 10.1136/bmj.39489.470347.AD
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Abstract
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE system, which is increasingly being adopted by organisations worldwide
Conflict of interest statement
Competing interests: All authors are involved in the dissemination of GRADE, and GRADE’s success has a positive influence on their academic career. Authors listed in the byline have received travel reimbursement and honorariums for presentations that included a review of GRADE’s approach to rating quality of evidence and grading recommendations. GHG acts as a consultant to UpToDate; his work includes helping UpToDate in their use of GRADE. HJS is documents editor and methodologist for the American Thoracic Society; one of his roles in these positions is helping implement the use of GRADE. He is supported by “The human factor, mobility and Marie Curie actions scientist reintegration European Commission grant: IGR 42192—GRADE.”
Figures
Similar articles
-
[Evidence-based medicine is gold standard for medical guidelines].Psychiatr Prax. 2011 Jul;38(5):218-20. doi: 10.1055/s-0031-1276830. Epub 2011 Jun 21. Psychiatr Prax. 2011. PMID: 21695665 German. No abstract available.
-
Rating the quality of evidence and the strength of recommendations using GRADE.World J Urol. 2011 Jun;29(3):311-7. doi: 10.1007/s00345-011-0667-2. Epub 2011 Mar 9. World J Urol. 2011. PMID: 21387101 Review.
-
[GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations].Z Evid Fortbild Qual Gesundhwes. 2014;108(7):413-20. doi: 10.1016/j.zefq.2014.08.003. Epub 2014 Sep 16. Z Evid Fortbild Qual Gesundhwes. 2014. PMID: 25444300 German.
-
Consistent Definitions of Clinical Practice Guidelines, Consensus Statements, Position Statements, and Practice Alerts.Anesth Analg. 2019 Dec;129(6):1767-1770. doi: 10.1213/ANE.0000000000004236. Anesth Analg. 2019. PMID: 31743199 Review.
-
GRADE guidelines: 10. Considering resource use and rating the quality of economic evidence.J Clin Epidemiol. 2013 Feb;66(2):140-50. doi: 10.1016/j.jclinepi.2012.04.012. Epub 2012 Aug 3. J Clin Epidemiol. 2013. PMID: 22863410 Review.
Cited by
-
Effectiveness of concentrated growth factors with or without grafting materials in maxillary sinus augmentation: a systematic review.BMC Oral Health. 2024 Oct 24;24(1):1275. doi: 10.1186/s12903-024-04952-w. BMC Oral Health. 2024. PMID: 39448954 Free PMC article.
-
Safety and tolerability of natural and synthetic cannabinoids in adults aged over 50 years: A systematic review and meta-analysis.PLoS Med. 2021 Mar 29;18(3):e1003524. doi: 10.1371/journal.pmed.1003524. eCollection 2021 Mar. PLoS Med. 2021. PMID: 33780450 Free PMC article.
-
Interventions for atypical haemolytic uraemic syndrome.Cochrane Database Syst Rev. 2021 Mar 23;3(3):CD012862. doi: 10.1002/14651858.CD012862.pub2. Cochrane Database Syst Rev. 2021. PMID: 33783815 Free PMC article.
-
Vaccines for preventing enterotoxigenic Escherichia coli (ETEC) diarrhoea.Cochrane Database Syst Rev. 2013 Jul 5;2013(7):CD009029. doi: 10.1002/14651858.CD009029.pub2. Cochrane Database Syst Rev. 2013. PMID: 23828581 Free PMC article. Review.
-
Efficacy and safety of total glucosides of paeony as an add-on treatment in adolescents and adults with chronic urticaria: A systematic review and meta-analysis.Front Pharmacol. 2022 Sep 23;13:961371. doi: 10.3389/fphar.2022.961371. eCollection 2022. Front Pharmacol. 2022. PMID: 36263138 Free PMC article.
References
-
- Lacchetti C, Guyatt G. Surprising results of randomized trials. In: Guyatt G, Drummond R, eds. Users’ guides to the medical literature: a manual of evidence-based clinical practice Chicago, IL: AMA Press, 2002
-
- American College of Physicians. Guidelines for counseling postmenopausal women about preventive hormone therapy. Ann Intern Med 1992;117:1038-41. - PubMed
-
- Humphrey LL, Chan BK, Sox HC. Postmenopausal hormone replacement therapy and the primary prevention of cardiovascular disease. Ann Intern Med 2002;137:273-84. - PubMed
-
- Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA 1998;280:605-13. - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources