Probability of stroke: a risk profile from the Framingham Study
- PMID: 2003301
- DOI: 10.1161/01.str.22.3.312
Probability of stroke: a risk profile from the Framingham Study
Abstract
A health risk appraisal function has been developed for the prediction of stroke using the Framingham Study cohort. The stroke risk factors included in the profile are age, systolic blood pressure, the use of antihypertensive therapy, diabetes mellitus, cigarette smoking, prior cardiovascular disease (coronary heart disease, cardiac failure, or intermittent claudication), atrial fibrillation, and left ventricular hypertrophy by electrocardiogram. Based on 472 stroke events occurring during 10 years' follow-up from biennial examinations 9 and 14, stroke probabilities were computed using the Cox proportional hazards model for each sex based on a point system. On the basis of the risk factors in the profile, which can be readily determined on routine physical examination in a physician's office, stroke risk can be estimated. An individual's risk can be related to the average risk of stroke for persons of the same age and sex. The information that one's risk of stroke is several times higher than average may provide the impetus for risk factor modification. It may also help to identify persons at substantially increased stroke risk resulting from borderline levels of multiple risk factors such as those with mild or borderline hypertension and facilitate multifactorial risk factor modification.
Similar articles
-
Comparison of probability of stroke between the Copenhagen City Heart Study and the Framingham Study.Stroke. 1994 Apr;25(4):802-7. doi: 10.1161/01.str.25.4.802. Stroke. 1994. PMID: 8160224
-
Stroke risk profile: adjustment for antihypertensive medication. The Framingham Study.Stroke. 1994 Jan;25(1):40-3. doi: 10.1161/01.str.25.1.40. Stroke. 1994. PMID: 8266381
-
Left ventricular mass and risk of stroke in an elderly cohort. The Framingham Heart Study.JAMA. 1994 Jul 6;272(1):33-6. JAMA. 1994. PMID: 8007076
-
Hypertension as a risk factor for cardiac events--epidemiologic results of long-term studies.J Cardiovasc Pharmacol. 1993;21 Suppl 2:S27-37. doi: 10.1097/00005344-199321002-00006. J Cardiovasc Pharmacol. 1993. PMID: 7692148 Review.
-
Risk factors for geriatric stroke: identification and follow-up.Geriatrics. 1990 Sep;45(9):37-40, 43-4. Geriatrics. 1990. PMID: 2204586 Review.
Cited by
-
A 5-Year Mortality Prediction Model for Prostate Cancer Patients Based on the Korean Nationwide Health Insurance Claims Database.J Pers Med. 2024 Oct 13;14(10):1058. doi: 10.3390/jpm14101058. J Pers Med. 2024. PMID: 39452565 Free PMC article.
-
Laboratory tests as short-term correlates of stroke.BMC Neurol. 2016 Jul 21;16:112. doi: 10.1186/s12883-016-0619-y. BMC Neurol. 2016. PMID: 27439507 Free PMC article.
-
New therapeutic _targets in cardiology: arrhythmias and Ca2+/calmodulin-dependent kinase II (CaMKII).Circulation. 2012 Oct 23;126(17):2125-39. doi: 10.1161/CIRCULATIONAHA.112.124990. Circulation. 2012. PMID: 23091085 Free PMC article. Review. No abstract available.
-
Sex and Race Differences in the Risk of Ischemic Stroke Associated With Fasting Blood Glucose in REGARDS.Neurology. 2021 Aug 17;97(7):e684-e694. doi: 10.1212/WNL.0000000000012296. Epub 2021 May 27. Neurology. 2021. PMID: 34045272 Free PMC article.
-
Vascular risk factors and cardiovascular outcomes in the Alzheimer's disease neuroimaging initiative.Am J Alzheimers Dis Other Demen. 2012 Jun;27(4):275-9. doi: 10.1177/1533317512449730. Am J Alzheimers Dis Other Demen. 2012. PMID: 22739032 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
