Cardiovascular outcomes in randomized trials: should time to first event for "hard" end points remain the standard approach?
- PMID: 20082924
- DOI: 10.1016/j.jacc.2009.09.021
Cardiovascular outcomes in randomized trials: should time to first event for "hard" end points remain the standard approach?
Comment on
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Total cardiovascular disease burden: comparing intensive with moderate statin therapy insights from the IDEAL (Incremental Decrease in End Points Through Aggressive Lipid Lowering) trial.J Am Coll Cardiol. 2009 Dec 15;54(25):2353-7. doi: 10.1016/j.jacc.2009.08.035. J Am Coll Cardiol. 2009. PMID: 20082922 Clinical Trial.
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Reduction in recurrent cardiovascular events with intensive lipid-lowering statin therapy compared with moderate lipid-lowering statin therapy after acute coronary syndromes from the PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) trial.J Am Coll Cardiol. 2009 Dec 15;54(25):2358-62. doi: 10.1016/j.jacc.2009.10.005. J Am Coll Cardiol. 2009. PMID: 20082923 Clinical Trial.
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