Comment
doi: 10.1016/j.chom.2010.08.008.
Epithelial sensing of fungal invasion
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- PMID: 20833371
- DOI: 10.1016/j.chom.2010.08.008
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Comment
Epithelial sensing of fungal invasion
Cell Host Microbe.
.
Free article
Abstract
The mechanisms discriminating mucosal colonization from invasion by Candida albicans are unclear. In this issue, Moyes et al. show that epithelial cells discriminate between colonizing yeasts and invading hyphae by mechanisms involving c-Fos and MKP1 phosphatase, opening up new avenues for understanding the pathophysiology of mucosal fungal infections.
Copyright © 2010 Elsevier Inc. All rights reserved.
Comment on
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A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells.Cell Host Microbe. 2010 Sep 16;8(3):225-35. doi: 10.1016/j.chom.2010.08.002. Cell Host Microbe. 2010. PMID: 20833374 Free PMC article.
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