Fatigue, sleep-wake disturbances, and quality of life in adolescents receiving chemotherapy
- PMID: 21063224
- DOI: 10.1097/MPH.0b013e3181f46a46
Fatigue, sleep-wake disturbances, and quality of life in adolescents receiving chemotherapy
Abstract
Background: Adolescents with cancer experience distressing physical and psychosocial symptoms, especially during treatment. Fatigue and sleep disturbances commonly affect adolescents' quality of life, but little is known about how adolescents experience these symptoms during an early month of chemotherapy. This study measured fatigue, sleep disturbances, and quality of life in 20 adolescents over 1 month while they were receiving chemotherapy.
Methods: Multidimensional fatigue and quality of life were measured weekly with modules from the PedsQL Measurement Model, and sleep disturbances were measured with the General Sleep Disturbance Scale.
Results: Adolescents experienced increased severity of fatigue and sleep disturbances during the week after treatment. Common sleep-wake problems included daytime sleepiness, decreased alertness, and poor sleep quality. Fatigue and sleep-wake disturbances were related symptoms, and both symptoms were associated with various domains of quality of life.
Conclusions: Fatigue and sleep-wake disturbances are significant problems for adolescents receiving chemotherapy and negatively affect the quality of life. Clinicians should routinely screen adolescent patients for fatigue and sleep disturbances and intervene to minimize their impact using pharmacologic and nonpharmacologic strategies.
Similar articles
-
A Systematic Review of Sleep-Wake Disturbances in Childhood Traumatic Brain Injury: Relationship with Fatigue, Depression, and Quality of Life.J Head Trauma Rehabil. 2019 Jul/Aug;34(4):241-256. doi: 10.1097/HTR.0000000000000446. J Head Trauma Rehabil. 2019. PMID: 30499928
-
Symptoms in Children Receiving Treatment for Cancer-Part I: Fatigue, Sleep Disturbance, and Nausea/Vomiting.J Pediatr Oncol Nurs. 2019 Jul/Aug;36(4):244-261. doi: 10.1177/1043454219849576. J Pediatr Oncol Nurs. 2019. PMID: 31307321 Free PMC article. Review.
-
The longitudinal relationship between fatigue and sleep in breast cancer patients undergoing chemotherapy.Sleep. 2012 Feb 1;35(2):237-45. doi: 10.5665/sleep.1630. Sleep. 2012. PMID: 22294814 Free PMC article.
-
Patterns of fatigue in adolescents receiving chemotherapy.Oncol Nurs Forum. 2010 Jul;37(4):444-55. doi: 10.1188/10.ONF.444-455. Oncol Nurs Forum. 2010. PMID: 20591804
-
Modifying cancer-related fatigue by optimizing sleep quality.J Natl Compr Canc Netw. 2008 Jan;6(1):3-13. doi: 10.6004/jnccn.2008.0002. J Natl Compr Canc Netw. 2008. PMID: 18267055 Review.
Cited by
-
Evaluation of health-related quality of life and its domains in pediatric patients with cancer.J Egypt Natl Canc Inst. 2023 Apr 17;35(1):9. doi: 10.1186/s43046-023-00168-1. J Egypt Natl Canc Inst. 2023. PMID: 37062773
-
Longitudinal course and risk factors for fatigue in adolescents: the mediating role of sleep disturbances.J Pediatr Psychol. 2013 Nov;38(10):1070-80. doi: 10.1093/jpepsy/jst051. Epub 2013 Jul 16. J Pediatr Psychol. 2013. PMID: 23860262 Free PMC article.
-
Prevalence, putative mechanisms, and current management of sleep problems during chemotherapy for cancer.Nat Sci Sleep. 2012 Dec 17;4:151-162. doi: 10.2147/NSS.S18895. Nat Sci Sleep. 2012. PMID: 23486503 Free PMC article.
-
Considering quality of life for children with cancer: a systematic review of patient-reported outcome measures and the development of a conceptual model.Qual Life Res. 2014 Apr;23(3):771-89. doi: 10.1007/s11136-013-0482-x. Epub 2013 Aug 2. Qual Life Res. 2014. PMID: 23907613 Review.
-
A pilot exploration of symptom trajectories in adolescents with cancer during chemotherapy.Cancer Nurs. 2013 Jan-Feb;36(1):60-71. doi: 10.1097/NCC.0b013e318250da1a. Cancer Nurs. 2013. PMID: 22561919 Free PMC article.
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical
