Co-occurring depression and pain in multiple sclerosis

doi:10.1016/j.pmr.2013.06.001

Review

. 2013 Nov;24(4):703-15.

doi: 10.1016/j.pmr.2013.06.001. Epub 2013 Jul 23.

Co-occurring depression and pain in multiple sclerosis

Kevin N Alschuler¹, Dawn M Ehde, Mark P Jensen

Affiliations

Affiliation

¹ Department of Rehabilitation Medicine, University of Washington School of Medicine, Box 358815, 1536 North 115th Street, Seattle, WA 98133, USA. Electronic address: kalschul@uw.edu.

PMID: 24314687
PMCID: PMC3857561
DOI: 10.1016/j.pmr.2013.06.001

Review

Co-occurring depression and pain in multiple sclerosis

Kevin N Alschuler et al. Phys Med Rehabil Clin N Am. 2013 Nov.

. 2013 Nov;24(4):703-15.

doi: 10.1016/j.pmr.2013.06.001. Epub 2013 Jul 23.

Authors

Kevin N Alschuler¹, Dawn M Ehde, Mark P Jensen

Affiliation

¹ Department of Rehabilitation Medicine, University of Washington School of Medicine, Box 358815, 1536 North 115th Street, Seattle, WA 98133, USA. Electronic address: kalschul@uw.edu.

PMID: 24314687
PMCID: PMC3857561
DOI: 10.1016/j.pmr.2013.06.001

Abstract

Depression and pain are highly prevalent among individuals with multiple sclerosis, and they often co-occur. The purpose of this article is to summarize the literature and theory related to the comorbidity of pain and depression and describe how their presence can impact individuals with multiple sclerosis. Additionally, the article discusses how existing treatments of pain and depression could be adapted to address shared mechanisms and overcome barriers to treatment utilization.

Keywords: Depression; Multiple sclerosis; Pain.

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References

1. Ehde DM, Osborne TL, Jensen MP. Chronic pain in persons with multiple sclerosis. Phys Med Rehabil Clin N Am. 2005;16(2):503–12. - PubMed
1. Ehde DM, Bombardier CH. Depression in persons with multiple sclerosis. Phys Med Rehabil Clin N Am. 2005;16(2):437–48. ix. - PubMed
1. O’Connor AB, Schwid SR, Herrmann DN, Markman JD, Dworkin RH. Pain associated with multiple sclerosis: systematic review and proposed classification. Pain. 2008;137(1):96–111. - PubMed
1. Alschuler KN, Ehde DM, Jensen MP. The co-occurrence of pain and depression in adults with multiple sclerosis. Rehabilitation Psychology. In press. - PMC - PubMed
1. Alschuler KN, Jensen MP, Ehde DM. Defining mild, moderate, and severe pain in persons with multiple sclerosis. Pain Med. 2012;13(10):1358–65. - PMC - PubMed

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[1] Ehde DM, Osborne TL, Jensen MP. Chronic pain in persons with multiple sclerosis. Phys Med Rehabil Clin N Am. 2005;16(2):503–12. - PubMed

[2] Ehde DM, Osborne TL, Jensen MP. Chronic pain in persons with multiple sclerosis. Phys Med Rehabil Clin N Am. 2005;16(2):503–12. - PubMed

[3] Ehde DM, Bombardier CH. Depression in persons with multiple sclerosis. Phys Med Rehabil Clin N Am. 2005;16(2):437–48. ix. - PubMed

[4] Ehde DM, Bombardier CH. Depression in persons with multiple sclerosis. Phys Med Rehabil Clin N Am. 2005;16(2):437–48. ix. - PubMed

[5] O’Connor AB, Schwid SR, Herrmann DN, Markman JD, Dworkin RH. Pain associated with multiple sclerosis: systematic review and proposed classification. Pain. 2008;137(1):96–111. - PubMed

[6] O’Connor AB, Schwid SR, Herrmann DN, Markman JD, Dworkin RH. Pain associated with multiple sclerosis: systematic review and proposed classification. Pain. 2008;137(1):96–111. - PubMed

[7] Alschuler KN, Ehde DM, Jensen MP. The co-occurrence of pain and depression in adults with multiple sclerosis. Rehabilitation Psychology. In press. - PMC - PubMed

[8] Alschuler KN, Ehde DM, Jensen MP. The co-occurrence of pain and depression in adults with multiple sclerosis. Rehabilitation Psychology. In press. - PMC - PubMed

[9] Alschuler KN, Jensen MP, Ehde DM. Defining mild, moderate, and severe pain in persons with multiple sclerosis. Pain Med. 2012;13(10):1358–65. - PMC - PubMed

[10] Alschuler KN, Jensen MP, Ehde DM. Defining mild, moderate, and severe pain in persons with multiple sclerosis. Pain Med. 2012;13(10):1358–65. - PMC - PubMed

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Co-occurring depression and pain in multiple sclerosis

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Co-occurring depression and pain in multiple sclerosis

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