Cargo recognition and trafficking in selective autophagy

doi:10.1038/ncb2979

Review

. 2014 Jun;16(6):495-501.

doi: 10.1038/ncb2979.

Cargo recognition and trafficking in selective autophagy

Alexandra Stolz¹, Andreas Ernst¹, Ivan Dikic²

Affiliations

¹ Institute of Biochemistry II, Goethe University, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany.
² 1] Institute of Biochemistry II, Goethe University, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany [2] Buchmann Institute for Molecular Life Sciences, Max-von-Laue-Straße 15, D-60438 Frankfurt am Main, Germany.

PMID: 24875736
DOI: 10.1038/ncb2979

Review

Cargo recognition and trafficking in selective autophagy

Alexandra Stolz et al. Nat Cell Biol. 2014 Jun.

. 2014 Jun;16(6):495-501.

doi: 10.1038/ncb2979.

Authors

Alexandra Stolz¹, Andreas Ernst¹, Ivan Dikic²

Affiliations

¹ Institute of Biochemistry II, Goethe University, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany.
² 1] Institute of Biochemistry II, Goethe University, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany [2] Buchmann Institute for Molecular Life Sciences, Max-von-Laue-Straße 15, D-60438 Frankfurt am Main, Germany.

PMID: 24875736
DOI: 10.1038/ncb2979

Abstract

Selective autophagy is a quality control pathway through which cellular components are sequestered into double-membrane vesicles and delivered to specific intracellular compartments. This process requires autophagy receptors that link cargo to growing autophagosomal membranes. Selective autophagy is also implicated in various membrane trafficking events. Here we discuss the current view on how cargo selection and transport are achieved during selective autophagy, and point out molecular mechanisms that are congruent between autophagy and vesicle trafficking pathways.

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References

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[1] Nat Cell Biol. 2012 Jan 22;14(2):177-85 - PubMed

[2] Nat Cell Biol. 2012 Jan 22;14(2):177-85 - PubMed

[3] Autophagy. 2007 Mar-Apr;3(2):106-16 - PubMed

[4] Autophagy. 2007 Mar-Apr;3(2):106-16 - PubMed

[5] Traffic. 2010 Apr;11(4):468-78 - PubMed

[6] Traffic. 2010 Apr;11(4):468-78 - PubMed

[7] Nat Cell Biol. 2011 Dec 04;14(1):51-60 - PubMed

[8] Nat Cell Biol. 2011 Dec 04;14(1):51-60 - PubMed

[9] Nat Cell Biol. 2010 Sep;12(9):836-41 - PubMed

[10] Nat Cell Biol. 2010 Sep;12(9):836-41 - PubMed

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Cargo recognition and trafficking in selective autophagy

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Cargo recognition and trafficking in selective autophagy

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