doi: 10.1039/c5cc05139h.
Epub 2015 Jul 24.
A BODIPY-based 'turn-on' fluorescent probe for hypoxic cell imaging
Affiliations
- PMID: 26207944
- DOI: 10.1039/c5cc05139h
Item in Clipboard
A BODIPY-based 'turn-on' fluorescent probe for hypoxic cell imaging
Chem Commun (Camb).
.
Abstract
A boron-dipyrromethene (BODIPY) dye containing a styryl substituent with a hydroxyl and nitro group, 1a, exhibits a 'turn-on' fluorescence response for hypoxic cells. The presence of the electron-withdrawing nitro group results in a highly efficient nonradiative decay of the S1 state, and hence a recovery of fluorescence intensity when nitro reduction occurs under hypoxic conditions.
Similar articles
-
Lysosome-_targeting turn-on red/NIR BODIPY probes for imaging hypoxic cells.Chem Commun (Camb). 2019 Sep 24;55(77):11567-11570. doi: 10.1039/c9cc04416g. Chem Commun (Camb). 2019. PMID: 31495830
-
Conformationally restricted dipyrromethene boron difluoride (BODIPY) dyes: highly fluorescent, multicolored probes for cellular imaging.Chemistry. 2008;14(19):5812-9. doi: 10.1002/chem.200800309. Chemistry. 2008. PMID: 18494008
-
A BODIPY-based turn-on fluorescent probe for the selective detection of hydrogen sulfide in solution and in cells.Talanta. 2015 Nov 1;144:763-8. doi: 10.1016/j.talanta.2015.07.026. Epub 2015 Jul 10. Talanta. 2015. PMID: 26452888
-
Lighting the way ahead with boron dipyrromethene (Bodipy) dyes.Phys Chem Chem Phys. 2009 Jun 7;11(21):4124-31. doi: 10.1039/b901383k. Epub 2009 Mar 26. Phys Chem Chem Phys. 2009. PMID: 19458813 Review.
-
Rigidization, preorientation and electronic decoupling--the 'magic triangle' for the design of highly efficient fluorescent sensors and switches.Chem Soc Rev. 2002 Mar;31(2):116-27. doi: 10.1039/b100604p. Chem Soc Rev. 2002. PMID: 12109205 Review.
Cited by
-
A nitroreductase responsive and photoactivated fluorescent probe for dual-controlled tumor hypoxia imaging.RSC Adv. 2022 Aug 23;12(37):23796-23800. doi: 10.1039/d2ra04004b. eCollection 2022 Aug 22. RSC Adv. 2022. PMID: 36093234 Free PMC article.
-
Synthesis and regioselective functionalization of perhalogenated BODIPYs.Org Biomol Chem. 2016 Jul 14;14(26):6184-8. doi: 10.1039/c6ob00935b. Epub 2016 Jun 2. Org Biomol Chem. 2016. PMID: 27251595 Free PMC article.
-
Mechanochemical generation of singlet oxygen.RSC Adv. 2020 Mar 2;10(16):9182-9186. doi: 10.1039/d0ra00831a. eCollection 2020 Mar 2. RSC Adv. 2020. PMID: 35497229 Free PMC article.
-
Controllable Photodynamic Therapy Implemented by Regulating Singlet Oxygen Efficiency.Adv Sci (Weinh). 2017 Jun 23;4(7):1700113. doi: 10.1002/advs.201700113. eCollection 2017 Jul. Adv Sci (Weinh). 2017. PMID: 28725533 Free PMC article. Review.
-
Real-time monitoring of newly acidified organelles during autophagy enabled by reaction-based BODIPY dyes.Commun Biol. 2019 Nov 28;2:442. doi: 10.1038/s42003-019-0682-1. eCollection 2019. Commun Biol. 2019. PMID: 31815197 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
