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Multicenter Study
. 2015 Nov;110(2):193-201.
doi: 10.1016/j.diabres.2015.09.007. Epub 2015 Sep 18.

Social determinants of health in adults with type 2 diabetes--Contribution of mutable and immutable factors

Rebekah J Walker  1 , Brittany L Smalls  2 , Leonard E Egede  3
Affiliations
Multicenter Study

Social determinants of health in adults with type 2 diabetes--Contribution of mutable and immutable factors

Rebekah J Walker et al. Diabetes Res Clin Pract. 2015 Nov.

Abstract

Aims: Socioeconomic, psychosocial, and neighborhood factors influence clinical outcomes and self-care behaviors in diabetes; however, few studies simultaneously assessed the impact of multiple social determinant of health factors on glycemic control. We used an explanatory model to examine the differential contribution of social determinants and clinical factors on glycemic control. Secondarily, we examined the contribution of mutable and immutable factors to identify meaningful future interventions.

Methods: Six hundred and fifteen adults with type 2 diabetes in the southeastern United States were recruited. A hierarchical model was run with HbA1c as the dependent variable and independent variables entered in blocks: demographics (block 1), socioeconomic (block 2), psychosocial (block 3), built environment (block 4), clinical (block 5), and knowledge/self-care (block 6).

Results: Significant associations for HbA1c included self-efficacy (β=-0.10, p<0.001), social support (β=0.01, p<0.05), comorbidity (β=-0.09, p<0.05), insulin use (β=0.95, p<0.001), medication adherence (β=-0.11, p<0.05), and being a former smoker (β=0.34, p<0.05); accounting for 24.4% of the variance.

Conclusions: Important factors that drive glycemic control are mutable, and amenable to health interventions. Greater attention should be given to interventions that increase self-efficacy and social support, reduce the burden of comorbidities, and enhance medication adherence and smoking cessation.

Keywords: Built environment; Diabetes; Psychological; Social determinants; Socioeconomic.

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Conflict of interest statement

Conflict of Interest: The authors report no potential conflicts of interest relevant to this article.

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References

    1. Centers for Disease Control and Prevention. National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention; 2011.
    1. American Diabetes Association [ADA] Foundations of care: education, nutrition, physical activity, smoking cessation, psychosocial care, and immunization. Diabetes Care. 2015;38(Suppl 1):S20–S30. - PubMed
    1. American Diabetes Association [ADA] Strategies for improving care. Diabetes Care. 2015;38(Suppl 1):S5–S7. - PubMed
    1. Marmot M. Social determinants of health inequalities. Lancet. 2005;365:1099–1104. - PubMed
    1. Walker RJ, Smalls BL, Campbell JA, Strom Williams JL, Egede LE. Impact of social determinants of health on outcomes for type 2 diabetes: a systematic review. Endocrine. 2014;47(1):29–48. - PMC - PubMed

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