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Review
. 2016 Jun;5(3):288-300.
doi: 10.21037/tlcr.2016.06.07.

Non-small cell lung cancer: current treatment and future advances

Cecilia Zappa  1 , Shaker A Mousa  1
Affiliations
Review

Non-small cell lung cancer: current treatment and future advances

Cecilia Zappa et al. Transl Lung Cancer Res. 2016 Jun.

Abstract

Lung cancer has a poor prognosis; over half of people diagnosed with lung cancer die within one year of diagnosis and the 5-year survival is less than 18%. Non-small cell lung cancer (NSCLC) accounts for the majority of all lung cancer cases. Risk factors for developing NSCLC have been identified, with cigarette smoking being a major factor along with other environmental and genetic risk factors. Depending on the staging of lung cancer, patients are eligible for certain treatments ranging from surgery to radiation to chemotherapy as well as _targeted therapy. With the advancement of genetics and biomarkers testing, specific mutations have been identified to better _target treatment for individual patients. This review discusses current treatments including surgery, chemotherapy, radiotherapy, and immunotherapy as well as how biomarker testing has helped improve survival in patients with NSCLC.

Keywords: Chemotherapy; immunotherapy; non-small cell lung cancer (NSCLC).

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

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