Bone ingrowth into porous calcium phosphate ceramics: influence of pulsing electromagnetic field
- PMID: 2830390
- DOI: 10.1002/jor.1100060212
Bone ingrowth into porous calcium phosphate ceramics: influence of pulsing electromagnetic field
Abstract
The effect of a pulsing electromagnetic field (PEMF) on bone ingrowth into porous hydroxyapatite (HA) and porous tricalcium phosphate (TCP) implanted in rabbit tibiae was studied. To quantitate the biological response, a recently developed method of surface measurement using a scanning electron microscope was used. The morphometrical findings in the HA pores demonstrated a significantly greater amount of bone and thicker bone trabeculae in the PEMF group as compared with the nonpulsed control group at 3 to 4 weeks postimplantation. No significant differences for these parameters were found in the TCP pores. Histologically, more bone and wider bone trabeculae were observed in the HA implants for the PEMF-treated animals at the early time periods when compared with those of the control animals. Alternatively, the histological findings of the TCP implants were similar between these two groups. These histological results tended to correlate with the morphometrical data. Together, these results suggest that accelerated bone formation and bone maturation occurred in response to PEMF in the HA pores but was without effect in the TCP pores. This stimulatory effect is most significant after 3-4 weeks of PEMF stimulation.
Similar articles
-
Bone ingrowth into three different porous ceramics implanted into the tibia of rats and rabbits.J Orthop Res. 1985;3(1):65-77. doi: 10.1002/jor.1100030108. J Orthop Res. 1985. PMID: 2984392
-
Porous hydroxyapatite and tricalcium phosphate cylinders with two different pore size ranges implanted in the cancellous bone of rabbits. A comparative histomorphometric and histologic study of bony ingrowth and implant substitution.Clin Orthop Relat Res. 1988 Jul;(232):127-38. Clin Orthop Relat Res. 1988. PMID: 2838207
-
Bone ingrowth into two porous ceramics with different pore sizes: an experimental study.Acta Orthop Belg. 2004 Dec;70(6):598-603. Acta Orthop Belg. 2004. PMID: 15669463
-
[Integration properties of bone substitute materials. Experimental studies on animals].Orthopade. 1998 Feb;27(2):105-17. doi: 10.1007/s001320050208. Orthopade. 1998. PMID: 9530667 Review. German.
-
The effect of long-term pulsing electromagnetic field stimulation on experimental osteoporosis of rats.J UOEH. 1988 Mar 1;10(1):31-45. doi: 10.7888/juoeh.10.31. J UOEH. 1988. PMID: 3285429 Review.
Cited by
-
In Vitro Production of Calcified Bone Matrix onto Wool Keratin Scaffolds via Osteogenic Factors and Electromagnetic Stimulus.Materials (Basel). 2020 Jul 8;13(14):3052. doi: 10.3390/ma13143052. Materials (Basel). 2020. PMID: 32650489 Free PMC article.
-
Influence of surface microstructure on the reaction of the active ceramics in vivo.J Mater Sci Mater Med. 1998 Jul;9(7):381-4. doi: 10.1023/a:1013279412600. J Mater Sci Mater Med. 1998. PMID: 15348865
-
The quantification of bone tissue regeneration after electromagnetic stimulation.Arch Orthop Trauma Surg. 1993;112(2):75-8. doi: 10.1007/BF00420259. Arch Orthop Trauma Surg. 1993. PMID: 8457415
-
Harnessing electromagnetic fields to assist bone tissue engineering.Stem Cell Res Ther. 2023 Jan 11;14(1):7. doi: 10.1186/s13287-022-03217-z. Stem Cell Res Ther. 2023. PMID: 36631880 Free PMC article. Review.
-
Effect of Magnetic Field on Bone Healing around Endosseous Implants - An In-vivo Study.J Clin Diagn Res. 2016 Oct;10(10):ZF01-ZF04. doi: 10.7860/JCDR/2016/21509.8666. Epub 2016 Oct 1. J Clin Diagn Res. 2016. PMID: 27891492 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
