Triterpenoids and lignans from the stems of Schisandra glaucescens
- PMID: 29527951
- DOI: 10.1080/14786419.2018.1448980
Triterpenoids and lignans from the stems of Schisandra glaucescens
Abstract
Two new triterpenoids, 24( E)-3 α,12 α-dihydroxyl-lanost-9(11),24-dien-26-oid acid (1) and 3,4- seco-24( Z)-6 α,7 β-dihydroxyl-cycloart-4(28),24-dien-3,26-dioic-3-methyl ester (2), and ten known ones (3-12), together with eight lignans (13-20), were isolated from the stems of Schisandra glaucescens. Their structures were established on the basis of extensive spectroscopic analyses. Compounds 1-3, 5-7, 9, 11-13 and 15-18 were isolated from this species for the first time. 1 and 2 were evaluated for their in vitro cytotoxicities against the mouse cancer B16 cell line, human cancer HepG2 and MCF7 cell lines by MTT assay.
Keywords: cytotoxicity; lignans; triterpenoids.
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