The YOUth study: Rationale, design, and study procedures

doi:10.1016/j.dcn.2020.100868

. 2020 Dec:46:100868.

doi: 10.1016/j.dcn.2020.100868. Epub 2020 Oct 7.

The YOUth study: Rationale, design, and study procedures

Affiliations

¹ Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands. Electronic address: n.c.onland@umcutrecht.nl.
² Faculty of Social and Behavioural Sciences, Utrecht University, Utrecht, the Netherlands.
³ Division of Woman and Baby, University Medical Center Utrecht, Utrecht University, the Netherlands; Division of Biomedical Genetics, University Medical Center Utrecht, Utrecht University, the Netherlands.
⁴ UMC Utrecht Brain Center, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands.
⁵ Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, the Netherlands; Developmental Psychology, Utrecht University, Utrecht, the Netherlands.
⁶ Division of Woman and Baby, University Medical Center Utrecht, Utrecht University, the Netherlands.
⁷ Dept. Clinical Child and Family Studies, Social and Behavioral Sciences, Utrecht Univerity, Utrecht, the Netherlands.
⁸ UMC Utrecht Brain Center, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands; Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, the Netherlands; Developmental Psychology, Utrecht University, Utrecht, the Netherlands.

PMID: 33075722
PMCID: PMC7575850
DOI: 10.1016/j.dcn.2020.100868

The YOUth study: Rationale, design, and study procedures

N Charlotte Onland-Moret et al. Dev Cogn Neurosci. 2020 Dec.

. 2020 Dec:46:100868.

doi: 10.1016/j.dcn.2020.100868. Epub 2020 Oct 7.

Authors

Affiliations

¹ Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands. Electronic address: n.c.onland@umcutrecht.nl.
² Faculty of Social and Behavioural Sciences, Utrecht University, Utrecht, the Netherlands.
³ Division of Woman and Baby, University Medical Center Utrecht, Utrecht University, the Netherlands; Division of Biomedical Genetics, University Medical Center Utrecht, Utrecht University, the Netherlands.
⁴ UMC Utrecht Brain Center, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands.
⁵ Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, the Netherlands; Developmental Psychology, Utrecht University, Utrecht, the Netherlands.
⁶ Division of Woman and Baby, University Medical Center Utrecht, Utrecht University, the Netherlands.
⁷ Dept. Clinical Child and Family Studies, Social and Behavioral Sciences, Utrecht Univerity, Utrecht, the Netherlands.
⁸ UMC Utrecht Brain Center, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands; Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, the Netherlands; Developmental Psychology, Utrecht University, Utrecht, the Netherlands.

PMID: 33075722
PMCID: PMC7575850
DOI: 10.1016/j.dcn.2020.100868

Abstract

Behavioral development in children shows large inter-individual variation, and is driven by the interplay between biological, psychological, and environmental processes. However, there is still little insight into how these processes interact. The YOUth cohort specifically focuses on two core characteristics of behavioral development: social competence and self-regulation. Social competence refers to the ability to engage in meaningful interactions with others, whereas self-regulation is the ability to control one's emotions, behavior, and impulses, to balance between reactivity and control of the reaction, and to adjust to the prevailing environment. YOUth is an accelerated population-based longitudinal cohort study with repeated measurements, centering on two groups: YOUth Baby & Child and YOUth Child & Adolescent. YOUth Baby & Child aims to include 3,000 pregnant women, their partners and children, wheras YOUth Child & Adolescent aims to include 2,000 children aged between 8 and 10 years old and their parents. All participants will be followed for at least 6 years, and potentially longer. In this paper we describe in detail the design of this study, the population included, the determinants, intermediate neurocognitive measures and outcomes included in the study. Furthermore, we describe in detail the procedures of inclusion, informed consent, and study participation.

Keywords: Birth cohort; Cognitive development; Longitudinal cohorts study; Mental health; Self-regulation; Social competence.

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Conflict of interest statement

The authors report no declarations of interest.

Figures

**Fig. 2**
YOUth study design. ‘Around pregnancy’: 20–24 weeks of pregnancy and 29–33 weeks of pregnancy. Around 0’: 4–6 months and 9–11 months. ‘Around 3’: 2–4 years. ‘Around 6’: 5–7 years. ‘Around 9’: 8–10 years. ‘Around 12’: 11–13 years. ‘Around 15’: 14–16 years.

**Fig. 3**
Example test days for YOUth Baby & Child.

**Fig. 4**
example test days for YOUth Child & Adolescent.

See this image and copyright information in PMC

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References

1. Abidin R.R. CPPC Tests; Charlottesville: 1983. Parenting Stress Index--Manual (PSI)
1. Achenbach T.M., Rescorla L.A. In: Manual for the ASEBA Adult Forms & Profiles. R.C.f.C. University of Vermont, Youth, and Families, editor. 2003. Burlington, VT.
1. Albers M. Intra- and interobserver agreement for fetal cerebral measurements in 3D-ultrasonography. Hum. Brain Mapp. 2018;39(8):3277–3284. - PMC - PubMed
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1. Arnett A.B. The SWAN captures variance at the negative and positive ends of the ADHD symptom dimension. J. Atten. Disord. 2013;17(2):152–162. - PMC - PubMed

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[1] Abidin R.R. CPPC Tests; Charlottesville: 1983. Parenting Stress Index--Manual (PSI)

[2] Abidin R.R. CPPC Tests; Charlottesville: 1983. Parenting Stress Index--Manual (PSI)

[3] Achenbach T.M., Rescorla L.A. In: Manual for the ASEBA Adult Forms & Profiles. R.C.f.C. University of Vermont, Youth, and Families, editor. 2003. Burlington, VT.

[4] Achenbach T.M., Rescorla L.A. In: Manual for the ASEBA Adult Forms & Profiles. R.C.f.C. University of Vermont, Youth, and Families, editor. 2003. Burlington, VT.

[5] Albers M. Intra- and interobserver agreement for fetal cerebral measurements in 3D-ultrasonography. Hum. Brain Mapp. 2018;39(8):3277–3284. - PMC - PubMed

[6] Albers M. Intra- and interobserver agreement for fetal cerebral measurements in 3D-ultrasonography. Hum. Brain Mapp. 2018;39(8):3277–3284. - PMC - PubMed

[7] Ambrosino S. What can cortical development in attention-deficit/hyperactivity disorder teach us about the early developmental mechanisms involved? Cereb. Cortex. 2017;27(9):4624–4634. - PubMed

[8] Ambrosino S. What can cortical development in attention-deficit/hyperactivity disorder teach us about the early developmental mechanisms involved? Cereb. Cortex. 2017;27(9):4624–4634. - PubMed

[9] Arnett A.B. The SWAN captures variance at the negative and positive ends of the ADHD symptom dimension. J. Atten. Disord. 2013;17(2):152–162. - PMC - PubMed

[10] Arnett A.B. The SWAN captures variance at the negative and positive ends of the ADHD symptom dimension. J. Atten. Disord. 2013;17(2):152–162. - PMC - PubMed

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The YOUth study: Rationale, design, and study procedures

Affiliations

The YOUth study: Rationale, design, and study procedures

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Affiliations

Abstract

Conflict of interest statement

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