Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2021 Nov 14;47(1):226.
doi: 10.1186/s13052-021-01180-8.

Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study

Giovanni Savarino  1 , Maurizio Carta  2 , Marcello Cimador  2 , Antonio Corsello  3 , Mario Giuffrè  2 , Ingrid Anne Mandy Schierz  2 , Gregorio Serra  2 , Giovanni Corsello  2
Affiliations
Observational Study

Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study

Giovanni Savarino et al. Ital J Pediatr. .

Abstract

Necrotizing enterocolitis (NEC) is a typical disorder of preterm newborns, with a high mortality and morbidity rate. The therapeutic and nutritional management of disease depends on several factors. Its prognosis is linked, in addition to the severity of the disease and the need for surgery, to a correct enteral feeding in these patients. This study aims to identify the clinical characteristics of 18 patients with NEC, evaluating the different therapeutic paths undertaken, the type of formula used and the survival rate of this population. Average time of enteral nutrition before the NEC onset was 11,3 ± 11,6 days, with an average fasting period since the onset of 24 ± 18.9 days. 77.8% of patients received surgery and resumed enteral nutrition 17.7 ± 17.9 days after the intervention. The overall survival rate of our cohort was 55.5%. More prospective studies are needed to evaluate the long-term outcomes of survived children with NEC.

Keywords: Enteral formulas; NEC; Necrotizing enterocolitis; Neonatology; Pediatric gastroenterology; Pediatric nutrition; Pediatric surgery; Preterm newborns; Very low birth weight infants.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Patients for gestational age at birth (weeks) distribution
Fig. 2
Fig. 2
Born weight distribution (g)
Fig. 3
Fig. 3
Distribution enteral fasting days after NEC onset
Fig. 4
Fig. 4
Distribution of days between surgery and enteral re-feeding
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Neu J, Walker WA. Necrotizing enterocolitis. N Engl J Med. 2011;364(3):255–264. doi: 10.1056/NEJMra1005408. - DOI - PMC - PubMed
    1. Cutland CL, Lackritz EM, Mallett-Moore T, Bardají A, Chandrasekaran R, Lahariya C, et al. Low birth weight: Case definition & guidelines for data collection, analysis, and presentation of maternal immunization safety data. Vaccine. 2017;35(48Part A):6492–6500. doi: 10.1016/j.vaccine.2017.01.049. - DOI - PMC - PubMed
    1. Bell MJ, Ternberg JL, Feigin RD, Keating JP, Marshall R, Barton L, et al. Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging. Ann Surg. 1978;187(1):1–7. doi: 10.1097/00000658-197801000-00001. - DOI - PMC - PubMed
    1. Gregory KE, DeForge CE, Natale KM, Phillips M, Van Marter LJ. Necrotizing enterocolitis in the premature infant. Adv Neonatal Care. 2011;11(3):155–166. doi: 10.1097/ANC.0b013e31821baaf4. - DOI - PMC - PubMed
    1. Ou J, Courtney CM, Steinberger AE, Tecos ME, Warner BW. Nutrition in necrotizing enterocolitis and following intestinal resection. Nutrients. 2020;18(2):12(2). doi: 10.3390/nu12020520. - DOI - PMC - PubMed

Publication types

LinkOut - more resources

  NODES
admin 1
INTERN 4
twitter 2