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. 2024 May 13:38:e033.
doi: 10.1590/1807-3107bor-2024.vol38.0033. eCollection 2024.

Depressive symptoms and oral mucositis in children with oncological diseases: a cross-sectional study

Felipe Barreto Lemos  1 , Andressa Chang Fernandes Rodrigues da Silva  1 , Fernanda Pereira Lima  1 , Fernanda Conceição Machado  1 , Luanderson Lopes Pereira  1 , Arnaldo França Caldas  2 , Bruna Bustani Dos Santos  3 , Andréia Cristina Leal Figueiredo  1
Affiliations

Depressive symptoms and oral mucositis in children with oncological diseases: a cross-sectional study

Felipe Barreto Lemos et al. Braz Oral Res. .

Abstract

The aim of this study was to investigate the correlation between depressive symptoms and the occurrence of oral mucositis in children with oncological diseases treated at a reference hospital. This was a cross-sectional study conducted with individuals aged 4 to 18 years, diagnosed with primary neoplasms. Data was collected by using a questionnaire that assessed the degree of oral mucositis according to the World Health Organization index, the risk of oral mucositis according to the Child's International Mucositis Evaluation Scale, and depressive symptoms using the Children's Depression Inventory. The data were analyzed and subjected to Spearman's correlation, chi-square test, and Fisher's exact test, considering p<0.05. A statistically significant correlation was observed between depressive symptoms and the degree of oral mucositis (p = 0.044), and also between the "pain" variable within the risk of oral mucositis and depressive symptoms (p = 0.021). Based on the findings, it can be inferred that oral mucositis may be associated with the development of depressive symptoms and may be influenced by the individual's hospitalization, thereby affecting the quality of life of pediatric patients.

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Conflict of interest statement

Declaration of Interests: The authors certify that they have no commercial or associative interest that represents a conflict of interest in connection with the manuscript.

Figures

Figure 1
Figure 1. Correlations between variables. A. Correlation between depressive symptoms (CDI) and risk of oral mucositis (ChIMES); B. Correlation between depressive symptoms (CDI) and degree of oral mucositis (WHO scale); C. Correlation between depressive symptoms (CDI) and the subcategory “PAIN” (ChIMES); D. Correlation between depressive symptoms (CDI) and the subcategory “FUNCTION” (ChIMES).
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