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Review
. 2024 May 3;19(5):257-278.
doi: 10.1080/17460751.2024.2343555. Epub 2024 May 22.

Bioactive ceramic-based materials: beneficial properties and potential applications in dental repair and regeneration

Jiale Wang  1 , Linglin Zhang  1 , Kun Wang  1
Affiliations
Review

Bioactive ceramic-based materials: beneficial properties and potential applications in dental repair and regeneration

Jiale Wang et al. Regen Med. .

Abstract

Bioactive ceramics, primarily consisting of bioactive glasses, glass-ceramics, calcium orthophosphate ceramics, calcium silicate ceramics and calcium carbonate ceramics, have received great attention in the past decades given their biocompatible nature and excellent bioactivity in stimulating cell proliferation, differentiation and tissue regeneration. Recent studies have tried to combine bioactive ceramics with bioactive ions, polymers, bioactive proteins and other chemicals to improve their mechanical and biological properties, thus rendering them more valid in tissue engineering scaffolds. This review presents the beneficial properties and potential applications of bioactive ceramic-based materials in dentistry, particularly in the repair and regeneration of dental hard tissue, pulp-dentin complex, periodontal tissue and bone tissue. Moreover, greater insights into the mechanisms of bioactive ceramics and the development of ceramic-based materials are provided.

Keywords: bioactive ceramics; bone formation; dental hard tissue; periodontal regeneration; pulp–dentin complex regeneration.

Plain language summary

[Box: see text].

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Conflict of interest statement

The authors have no competing interests or relevant affiliations with any organization or entity with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, stock ownership or options and expert testimony.

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