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. 1979 Jan;16(1):25-30.
doi: 10.1007/BF00423146.

Worsening to diabetes in men with impaired glucose tolerance ("borderline diabetes")

R J Jarrett, H Keen, J H Fuller, M McCartney

Worsening to diabetes in men with impaired glucose tolerance ("borderline diabetes")

R J Jarrett et al. Diabetologia. 1979 Jan.

Abstract

Two hundred and four men with impaired glucose tolerance (borderline diabetes) discovered in a screening examination have been observed for five years and repeated tests of glucose tolerance performed. By pre-determined criteria 27 men 'worsened to diabetes' and this metabolic deterioration was not significantly influenced by treatment with carbohydrate restriction with or without a daily dose of 50 mg phenformin. Of the baseline variables measured prior to treatment allocation only the blood glucose values were significantly predictive of ultimate worsening to diabetes.

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