Review
doi: 10.1016/s0955-0674(96)80061-5.
Signal transduction through lipid second messengers
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- PMID: 8791422
- DOI: 10.1016/s0955-0674(96)80061-5
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Review
Signal transduction through lipid second messengers
Curr Opin Cell Biol.
1996 Apr.
Free article
Abstract
This review emphasizes the generation of glycerolipid and sphingolipid second messengers, and their molecular _targets. The role of the phosphatidylinositol transfer protein and phospholipase D in signal transmission, and the structures of the 1, 2-diacylglycerol and calcium-binding sites of protein kinase C are discussed. Further, ceramide signaling through protein kinases and the role of cross-talk in the signaling of apoptosis and inflammation are addressed.
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