Review
doi: 10.1016/s1074-5521(98)90615-9.
Caspases: key mediators of apoptosis
Affiliations
- PMID: 9578633
- DOI: 10.1016/s1074-5521(98)90615-9
Item in Clipboard
Review
Caspases: key mediators of apoptosis
Chem Biol.
1998 May.
Abstract
Recent studies have established that members of the caspase protease family are essential components of a conserved cell death program. Insights into their biological roles, structure and mechanism are enabling investigators to begin to explore the therapeutic potential of caspase inhibition.
Similar articles
-
Caspases: enemies within.Science. 1998 Aug 28;281(5381):1312-6. doi: 10.1126/science.281.5381.1312. Science. 1998. PMID: 9721091 Review.
-
ICE-like proteases and cell death.Behring Inst Mitt. 1996 Oct;(97):127-43. Behring Inst Mitt. 1996. PMID: 8950471 Review. No abstract available.
-
Interleukin-1 beta converting enzyme: a novel cysteine protease required for IL-1 beta production and implicated in programmed cell death.Protein Sci. 1995 Jan;4(1):3-12. doi: 10.1002/pro.5560040102. Protein Sci. 1995. PMID: 7773174 Free PMC article. Review.
-
Inhibition of distant caspase homologues by natural caspase inhibitors.Biochem J. 2001 Jul 15;357(Pt 2):575-80. doi: 10.1042/0264-6021:3570575. Biochem J. 2001. PMID: 11439111 Free PMC article.
-
Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis.J Biol Chem. 2011 Sep 30;286(39):34147-54. doi: 10.1074/jbc.M111.247627. Epub 2011 Aug 2. J Biol Chem. 2011. PMID: 21828056 Free PMC article.
Cited by
-
New therapies for hepatic fibrosis.Clin Res Hepatol Gastroenterol. 2015 Sep;39 Suppl 1(0 1):S75-9. doi: 10.1016/j.clinre.2015.06.011. Epub 2015 Jul 20. Clin Res Hepatol Gastroenterol. 2015. PMID: 26206573 Free PMC article. Review.
-
Differential expression of apoptosis related genes in selected strains of Aedes aegypti with different susceptibilities to dengue virus.PLoS One. 2013 Apr 10;8(4):e61187. doi: 10.1371/journal.pone.0061187. Print 2013. PLoS One. 2013. PMID: 23593426 Free PMC article.
-
Advancements in Genetic and Biochemical Insights: Unraveling the Etiopathogenesis of Neurodegeneration in Parkinson's Disease.Biomolecules. 2024 Jan 5;14(1):73. doi: 10.3390/biom14010073. Biomolecules. 2024. PMID: 38254673 Free PMC article. Review.
-
Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis.Nucleic Acids Res. 2000 Nov 1;28(21):4180-8. doi: 10.1093/nar/28.21.4180. Nucleic Acids Res. 2000. PMID: 11058115 Free PMC article.
-
Evidence for a Novel, Caspase-8-Independent, Fas Death Domain-Mediated Apoptotic Pathway.J Biomed Biotechnol. 2004;2004(1):41-51. doi: 10.1155/S1110724304308041. J Biomed Biotechnol. 2004. PMID: 15123887 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
