Review
doi: 10.1016/s0960-9822(98)70291-x.
Proteasome assembly: biting the hand
Affiliations
- PMID: 9651672
- DOI: 10.1016/s0960-9822(98)70291-x
Item in Clipboard
Review
Proteasome assembly: biting the hand
Curr Biol.
.
Free article
Abstract
Proteasome assembly is regulated to ensure the enzyme is inactive until its active sites are compartmentalized within an interior aqueous chamber. In yeast, this depends on a dedicated chaperone that is trapped within the nascent proteasome, and degraded on maturation of the proteolytic subunits.
Similar articles
-
The base of the proteasome regulatory particle exhibits chaperone-like activity.Nat Cell Biol. 1999 Aug;1(4):221-6. doi: 10.1038/12043. Nat Cell Biol. 1999. PMID: 10559920
-
Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assembly.EMBO Rep. 2003 Oct;4(10):959-63. doi: 10.1038/sj.embor.embor938. Epub 2003 Sep 12. EMBO Rep. 2003. PMID: 12973301 Free PMC article.
-
Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly.Cell. 1996 Sep 20;86(6):961-72. doi: 10.1016/s0092-8674(00)80171-3. Cell. 1996. PMID: 8808631
-
Substrate access and processing by the 20S proteasome core particle.Int J Biochem Cell Biol. 2003 May;35(5):606-16. doi: 10.1016/s1357-2725(02)00390-4. Int J Biochem Cell Biol. 2003. PMID: 12672453 Review.
-
The 26S proteasome: a molecular machine designed for controlled proteolysis.Annu Rev Biochem. 1999;68:1015-68. doi: 10.1146/annurev.biochem.68.1.1015. Annu Rev Biochem. 1999. PMID: 10872471 Review.
Cited by
-
Biofunctionalized dissolvable hydrogel microbeads enable efficient characterization of native protein complexes.Nat Commun. 2024 Oct 5;15(1):8633. doi: 10.1038/s41467-024-52948-5. Nat Commun. 2024. PMID: 39366952 Free PMC article.
-
Genome-scale analyses of butanol tolerance in Saccharomyces cerevisiae reveal an essential role of protein degradation.Biotechnol Biofuels. 2013 Apr 3;6(1):48. doi: 10.1186/1754-6834-6-48. Biotechnol Biofuels. 2013. PMID: 23552365 Free PMC article.
-
Modeling reveals the strength of weak interactions in stacked-ring assembly.Biophys J. 2024 Jul 2;123(13):1763-1780. doi: 10.1016/j.bpj.2024.05.015. Epub 2024 May 18. Biophys J. 2024. PMID: 38762753 Free PMC article.
-
Plasticity in eucaryotic 20S proteasome ring assembly revealed by a subunit deletion in yeast.EMBO J. 2004 Feb 11;23(3):500-10. doi: 10.1038/sj.emboj.7600059. Epub 2004 Jan 22. EMBO J. 2004. PMID: 14739934 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
