Prognostic factors in postraumatic severe diffuse brain injury
- PMID: 9932126
- DOI: 10.1007/s007010050247
Prognostic factors in postraumatic severe diffuse brain injury
Abstract
It is usually defficult in clinical practice to establish factors affecting final outcome in patients suffering severe diffuse brain injury (SDBI), due to the absence of specific semiology.
Methods: We studied retrospectively 160 consecutive patients with criteria of SDBI. We performed a statistical analysis of epidemiological, clinical and radiological factors, and relationship with final outcome.
Result: 35% of patients with severe head injury presented SDBI. Sixty percent were 15-35 year old and 73% male. More than 45% of the patients presented GCS 3 or 4. On CT performed during the first 24 h, haemorrhagic lesions appeared in white matter in 35% and subarachnoid haemorrhage was observed in 28%. During the first 24 h., 66% of patients presented values of intracranial pressure (ICP) above 20 mm Hg and a 33% below 20 mm Hg. Twenty percent of the patients had ICP > 20 mm and no response to treatment. According to the Glasgow Outcome Scale (GOS), mortality of more than 50% and 25% of patients with persistent vegetative state or severe disability were observed.
Conclusions: Clinical evaluation, early CT findings, ICP values and their response to medical treatment and clinical complications were found to be related (p < 0.05) to final outcome (GOS).
Similar articles
-
Analysis of long-term (median 10.5 years) outcomes in children presenting with traumatic brain injury and an initial Glasgow Coma Scale score of 3 or 4.J Neurosurg Pediatr. 2015 Oct;16(4):410-9. doi: 10.3171/2015.3.PEDS14679. Epub 2015 Jul 3. J Neurosurg Pediatr. 2015. PMID: 26140392
-
[Value of serial CT scanning and intracranial pressure monitoring for detecting new intracranial mass effect in severe head injury patients showing lesions type I-II in the initial CT scan].Neurocirugia (Astur). 2005 Jun;16(3):217-34. Neurocirugia (Astur). 2005. PMID: 16007322 Review. Spanish.
-
Predictors of outcome in civilians with gunshot wounds to the head upon presentation.J Neurosurg. 2014 Sep;121(3):645-52. doi: 10.3171/2014.5.JNS131872. Epub 2014 Jul 4. J Neurosurg. 2014. PMID: 24995781
-
Response to intracranial hypertension treatment as a predictor of death in patients with severe traumatic brain injury.J Neurosurg. 2011 May;114(5):1471-8. doi: 10.3171/2010.11.JNS101116. Epub 2011 Jan 7. J Neurosurg. 2011. PMID: 21214327
-
Prognostic factors in severe head injury.Surg Gynecol Obstet. 1984 Dec;159(6):597-604. Surg Gynecol Obstet. 1984. PMID: 6390762 Review.
Cited by
-
Traumatic brain injury and grey matter concentration: a preliminary voxel based morphometry study.J Neurol Neurosurg Psychiatry. 2005 Jul;76(7):984-8. doi: 10.1136/jnnp.2004.036210. J Neurol Neurosurg Psychiatry. 2005. PMID: 15965207 Free PMC article.
-
[Secondary decompression trepanation in progressive post-traumatic brain edema after primary decompressive craniotomy].Unfallchirurg. 2003 Oct;106(10):815-25. doi: 10.1007/s00113-003-0663-0. Unfallchirurg. 2003. PMID: 14652724 German.
-
Risk factors for mortality within first 24 hours of head injury.Indian J Pediatr. 2002 Jul;69(7):573-7. doi: 10.1007/BF02722680. Indian J Pediatr. 2002. PMID: 12173696
-
Single photon emission computed tomography scanning: A predictor of outcome in vegetative state of head injury.J Neurosci Rural Pract. 2011 Jan;2(1):12-6. doi: 10.4103/0976-3147.80079. J Neurosci Rural Pract. 2011. PMID: 21716866 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources