Desfechos Metabólicos De Pacientes Submetidos a Bypass Gástrico Em Y De Roux Em Um Hospital Universitário

Becker, Tatiana Scheuer; Ronsoni, Marcelo Fernando; Hohl, Alexandre; Lee, Simone van de Sande

doi:10.4322/2357-9730.50381

Cited by 1 publication

(3 citation statements)

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“…In relation to weight loss, our results are consistent with those described by Yip et al, who used a similar design of study and identical follow‐up time; and with the study by Becker et al, carried out at the same facility as of our study, including all patients who underwent gastric bypass in 2012, but without pairing of the groups with and without T2DM …”

Section: Discussionsupporting

confidence: 92%

“…In relation to weight loss, our results are consistent with those without T2DM. 13,23 Studies addressing conservative treatments for obesity (lifestyle modification with or without drug treatment) have suggested that patients with T2DM would have greater difficulty in losing weight when compared to patients without T2DM. 10,24,25 A study comparing patients with T2DM and their spouses without, after changing eating habits and behavioural treatment over a 20-week programme, found that the weight loss of spouses without T2DM was significantly greater than those of patients with T2DM.…”

Section: Discussionmentioning

confidence: 99%

“…Our study has also shown an improvement in the metabolic profile of patients as evidenced in previous studies, which demonstrated a reduction of fasting blood glucose levels and lipid profile after the surgical procedure, allowing a reduction or suspension of medication. 13,17,23,27,28 In this aspect, despite similar weight loss, patients with T2DM tend to benefit most from the improvement of metabolic profile induced by gastric bypass, as they usually have more pronounced changes at baseline. As for LDL, patients without T2DM showed a more significant improvement at the 12-month follow-up, which may be justified by the higher baseline levels of this lipoprotein in this group.…”

Section: Discussionmentioning

confidence: 99%

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Bariatric surgery‐induced weight loss in patients with and without type 2 diabetes mellitus

et al. 2020

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Summary Surgical treatment of obesity leads to weight loss and metabolic improvement, but it is unclear if the response differs between patients with and without type 2 diabetes. Retrospective cohort study comparing weight loss and metabolic outcomes between patients with and without type 2 diabetes, matched for body mass index (BMI), gender and age, 12 months after Roux‐en‐Y gastric bypass. Forty‐eight patients with type 2 diabetes (D) and 48 without type 2 diabetes (ND) were evaluated, 87.5% female, mean age 42.2 ± 0.9 years. The mean baseline weight and BMI of the D and ND groups were, respectively, 120.3 ± 21.6 vs 123.7 ± 20.8 kg (P = .45) and 47.2 ± 7.5 vs 47.2 ± 6.9 kg/m2 (P = .70). After 12 months, there was no significant difference in weight (40.4 ± 16.9 vs 44.1 ± 12.2 kg, P = .28) and BMI (15.8 ± 6.5 vs 16.9 ± 4.5 kg/m2, P = .26) variation between groups. The parameters that presented significant variation were (D vs ND): fasting blood glucose (41.6 ± 43.0 vs 12.7 ± 17.2 mg/dL, P < .01), HbA1c (1.8 ± 1.6 vs 0.6 ± 0.7%; P < .01), triglycerides (91.1 ± 100.4 vs 54.2 ± 43.8 mg/dL; P = .04), low‐density lipoprotein (27.2 ± 41.5 vs 37.5 ± 24.2 mg/dL; P < .01) and gamma glutamyl transferase (46.5 ± 55.3 vs 17.7 ± 11.9 UI/L; P = .04). Weight loss 12 months after a gastric bypass was similar in patients with and without type 2 diabetes, the greater metabolic benefits appearing in patients with type 2 diabetes as they had more pronounced changes at baseline.

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Section: Discussionsupporting

confidence: 92%