Izopentenil pirofosfat

Izopentenil pirofosfat
	(hydroxy-(3-methylbut-3-enoxy) phosphoryl)oxyphosphonic acid
Identifikacija
CAS registarski broj	358-71-4
PubChem	15983957
ChemSpider	13115335
MeSH	isopentenyl+pyrophosphate
ChEBI	128769
Jmol-3D slike	Slika 1
SMILES
	CC(=C)CCOP(=O)([O-])OP(=O)([O-])[O-]
InChI
	InChI=1S/C5H12O7P2/c1-5(2)3-4-11-14(9,10)12-13(6,7)8/h1,3-4H2,2H3,(H,9,10)(H2,6,7,8)/p-3 ; Kod: NUHSROFQTUXZQQ-UHFFFAOYSA-K InChI=1/C5H12O7P2/c1-5(2)3-4-11-14(9,10)12-13(6,7)8/h1,3-4H2,2H3,(H,9,10)(H2,6,7,8)/p-3; Kod: NUHSROFQTUXZQQ-DFZHHIFOAI
Svojstva
Molekulska formula	C5H12O7P2
Molarna masa	246.092
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Izopentenil pirofosfat (IPP) je intermedijar u klasičnom, HMG-CoA reduktaznom putu koji koriste organizmi u biosintezi terpena i terpenoida. IPP se formira iz acetil-CoA preko mavelonske kiseline. IPP se može zatim izomerizovati do dimetilalil pirofosfata enzimom izopentenil pirofosfat izomeraza.^[4]^[5]

IPP može biti sintetisan alternativnim ne-mevalonatnim putem izoprenoidne biosinteze. Pri tome se formira iz (E)-4-hidroksi-3-metil-but-2-enil pirofosfata (HMB-PP) dejstvom enzima HMB-PP reduktaza (LytB, IspH). Ne-mevalonatni put koriste mnoge bakterije, protozoe klase apicomplexa kao što su malarijski paraziti, i plastidi viših biljaka.

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Donald Voet, Judith G. Voet (2005). Biochemistry (3 izd.). Wiley. ISBN 978-0-471-19350-0.
↑ David L. Nelson, Michael M. Cox (2005). Principles of Biochemistry (4th izd.). New York: W. H. Freeman. ISBN 0-7167-4339-6.

Spoljašnje veze

Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[VoetBiochemistry3rd-4] Donald Voet, Judith G. Voet (2005). Biochemistry (3 izd.). Wiley. ISBN 978-0-471-19350-0.

[Lehninger-5] David L. Nelson, Michael M. Cox (2005). Principles of Biochemistry (4th izd.). New York: W. H. Freeman. ISBN 0-7167-4339-6.

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