Spliceosome

molecular machine that removes intron RNA from the primary transcript

A spliceosome is a complex of special RNA and protein subunits. Spliceosomes are amazingly complex molecular machines.[1] They remove introns from a transcribed pre-mRNA segment. This process is generally referred to as splicing.

Each spliceosome is composed of five small nuclear RNAs, (snRNA)s, and more than 50 proteins.[1]

References

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  1. 1.0 1.1 Staley JP, Guthrie C (1998). "Mechanical devices of the spliceosome: motors, clocks, springs, and things". Cell. 92 (3): 315–26. doi:10.1016/S0092-8674(00)80925-3. PMID 9476892. S2CID 6208113.


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