Glutation peroksidaza
Glutation peroksidaza (EC 1.11.1.9, GSH peroksidaza, selenium-glutationska peroksidaza, redukovani glutation peroksidaza) je enzim sa sistematskim imenom glutation:vodonik-peroksid oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glutation peroksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.11.1.9 | ||||||||
| CAS broj | 9013-66-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2 glutation + H2O2 glutation disulfid + 2H2O
Ovaj protein sadrži selenocisteinski ostatak. Steroid i lipidni hidroperoksidi mogu da deluju kao akceptori.
Reference
uredi- ^ Chaudiere, J. & Tappel, A.L. (1983). „Purification and characterization of selenium-glutathione peroxidase from hamster liver”. Arch. Biochem. Biophys. 226: 448—457. PMID 6227287.
- ^ Grossmann, A. & Wendel, A. (1983). „Non-reactivity of the selenoenzyme glutathione peroxidase with enzymatically hydroperoxidized phospholipids”. Eur. J. Biochem. 135: 549—552. PMID 6413205.
- ^ Nakamura, W., Hosoda, S. and Hayashi, K. (1974). „Purification and properties of rat liver glutathione peroxidase”. Biochim. Biophys. Acta. 358: 251—261.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
uredi- Glutathione+peroxidase na US National Library of Medicine Medical Subject Headings (MeSH)
