Gastriksin
Gastriksin (EC 3.4.23.3, pepsin C, pig parapepsin II, parapepsin II) je enzim.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Gastriksin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.23.3 | ||||||||
| CAS broj | 9012-71-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Ograničenija specifičnost od pepsina A, mada dolazi do preferentnog razlaganja Tyr- veza. Veoma je aktivan na hemoglobinu
Ovaj enzim se formira iz progastricsina.
Reference
уреди- ^ Ryle, A.P. (1970). „The porcine pepsins and pepsinogens”. Methods Enzymol. 19: 316—336.
- ^ Tang, J. (1970). „Gastricsin and pepsin”. Methods Enzymol. 19: 406—421.
- ^ Foltmann, B. (1981). „Gastric proteinases - structure, function, evolution and mechanism of action”. Essays Biochem. 17: 52—84. PMID 6795036.
- ^ Foltmann, B. & Jensen, A.L. (1982). „Human progastricsin - analysis of intermediates during activation into gastricsin and determination of the amino-acid sequence of the propart”. Eur. J. Biochem. 128: 63—70. PMID 6816595.
- ^ Martin, P., Trieu-Cuot, P., Collin, J.-C. and Ribadeau Dumas, B. (1982). „Purification and characterization of bovine gastricsin”. Eur. J. Biochem. 122: 31—39. PMID 6800788.
- ^ Reid, W.A., Vongsorasak, L., Svasti, J., Valler, M.J. and Kay, J. (1984). „Identification of the acid proteinase in human seminal fluid as a gastricsin originating in the prostate”. Cell Tissue Res. 236: 597—600. PMID 6432332.
- ^ Hayano, T., Sogawa, K., Ichihara, Y., Fujii-Kuriyama, Y. and Takahasi, K. (1988). „Primary structure of human pepsinogen C gene”. J. Biol. Chem. 263: 1382—1385. PMID 3335549.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Gastricsin на US National Library of Medicine Medical Subject Headings (MeSH)
