Malat dehidrogenaza
Malat dehidrogenaza (EC 1.1.1.37, L-malat dehidrogenaza, NAD-L-malat dehidrogenaza, malatna kiselina dehidrogenaza, NAD-zavisna malitna dehidrogenaza, NAD-malat dehidrogenaza, NAD-malatna dehidrogenaza, malat (NAD) dehidrogenaza, NAD-specifična malat dehidrogenaza, NAD-vezana malat dehidrogenaza, MDH, L-malat-NAD+ oksidoreduktaza) je enzim sa sistematskim imenom (S)-malat:NAD+ oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
Malat dehidrogenaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.1.1.37 | ||||||||
CAS broj | 9001-64-3 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- (S)-malat + NAD+ oksaloacetat + NADH + H+
Takođe oksiduje nekoliko drugih 2-hidroksidikarboksilnih kiselina.
Reference
уреди- ^ Banaszak, L.J. & Bradshaw, R.A. (1975). „Malate dehydrogenase”. Ур.: Boyer, P.D. The Enzymes. 11 (3rd изд.). New York: Academic Press. стр. 369—396.
- ^ Guha, A., Englard, S. and Listowsky, I. (1968). „Beef heart malic dehydrogenases. VII. Reactivity of sulfhydryl groups and conformation of the supernatant enzyme”. J. Biol. Chem. 243: 609—615. PMID 5637713.
- ^ McReynolds, M.S. & Kitto, G.B. (1970). „Purification and properties of Drosophila malate dehydrogenases”. Biochim. Biophys. Acta. 198: 165—175. PMID 4313528.
- ^ Wolfe, R.G. & Nielands, J.B. (1956). „Some molecular and kinetic properties of heart malic dehydrogenase”. J. Biol. Chem. 221: 61—69. PMID 13345798.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Malate+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)