Postmenopausal hormone replacement therapy and the vascular wall: Mechanisms of 17 β-estradio's effects on vascular biology
M Joswig, V Hach-Wunderle, R Ziegler… - Experimental and …, 1999 - thieme-connect.com
Summary 17 β-estradiol (E 2) protects against atherosclerosis independent of changes in
plasma lipoproteins in a variety of animal models, which is explained by direct effects of E 2
on the vascular wall. E 2 improves vasomotion by modulation of vasoconstrictor and
vasodilator systems through endothelium-dependent and endothelium-independent
mechanisms. E 2 affects the remodeling of the vascular wall by inhibiting smooth muscle cell
proliferation and accelerating reendothelialization of injured blood vessels. E 2 modulates …
plasma lipoproteins in a variety of animal models, which is explained by direct effects of E 2
on the vascular wall. E 2 improves vasomotion by modulation of vasoconstrictor and
vasodilator systems through endothelium-dependent and endothelium-independent
mechanisms. E 2 affects the remodeling of the vascular wall by inhibiting smooth muscle cell
proliferation and accelerating reendothelialization of injured blood vessels. E 2 modulates …