Heading Abstract Aims/hypothesis. The molecular factors that cause an acute wound in
diabetic patients to become chronic have not yet been established. Wound healing is known
to require a balance between the accumulation of collagenous and non-collagenous
extracellular matrix components and their remodelling by matrix metalloproteinases (MMPs)
and the tissue inhibitors of metalloproteinases (TIMPs). Our aim was to assess if the
concentrations of MMPs and TIMPs were different between acute and chronic wounds in …